38862-29-2

Usage

Uses

Used in Chemical Synthesis Industry:
2-chloro-4-amino-1,3,5-triazine-6(5H)-one is used as a key intermediate for the preparation of substituted melamine, ammelides, and ammelines. These compounds have a wide range of applications in various industries, including plastics, coatings, adhesives, and flame retardants.
Used in Plastics Industry:
2-chloro-4-amino-1,3,5-triazine-6(5H)-one is used as a building block for the synthesis of melamine-based resins, which are known for their excellent heat resistance, rigidity, and chemical resistance. These resins are widely used in the production of high-performance plastics and molded products.
Used in Coatings and Adhesives Industry:
2-chloro-4-amino-1,3,5-triazine-6(5H)-one is used as a component in the formulation of melamine-formaldehyde resins, which are used as binders in coatings and adhesives. These resins provide excellent adhesion, water resistance, and durability to the final products.
Used in Flame Retardants Industry:
2-chloro-4-amino-1,3,5-triazine-6(5H)-one is used in the production of halogenated melamine compounds, which are effective flame retardants. These compounds are used in various applications, such as textiles, plastics, and rubber, to improve their fire resistance and safety properties.

InChI:InChI=1/C3H3ClN4O/c4-1-6-2(5)8-3(9)7-1/h(H3,5,6,7,8,9)

Upstream product

• 933-20-0 4,6-dichloro-1,3,5-triazin-2-amine 
• 108-77-0 1,3,5-trichloro-2,4,6-triazine 

Downstream Products

• 67410-53-1 C₇H₁₃N₅O₃ 
• 67410-53-1 2-amino-4-(2,2-dimethoxyethylamino)-s-triazin-6-one 

Relevant academic research and scientific papers

The surprising pairing of 2-aminoimidazo[1,2-a][1,3,5]triazin-4-one, a component of an expanded DNA alphabet

Synthetic biologists demonstrate their command over natural biology by reproducing the behaviors of natural living systems on synthetic biomolecular platforms. For nucleic acids, this is being done stepwise, first by adding replicable nucleotides to DNA, and then removing its standard nucleotides. This challenge has been met in vitro with `six-letter' DNA and RNA, where the Watson–Crick pairing `concept' is recruited to increase the number of independently replicable nucleotides from four to six. The two nucleobases most successfully added so far are Z and P, which present a donor–donor–acceptor and an acceptor–acceptor–donor pattern, respectively. This pair of nucleobases are part of an `artificially expanded genetic information system' (AEGIS). The Z nucleobase has been already crystallized, characterized, and published in this journal [Matsuura et al. (2016). Acta Cryst. C72, 952–959]. More recently, variants of Taq polymerase have been crystallized with the pair P:Z trapped in the active site. Here we report the crystal structure of the nucleobase 2-aminoimidazo[1,2-a][1,3,5]triazin-4-one (trivially named P) as the monohydrate, C5H5N5O·H2O. The nucleobase P was crystallized from water and characterized by X-ray diffraction. Interestingly, the crystal structure shows two tautomers of P packed in a Watson–Crick fashion that cocrystallized in a 1:1 ratio.

Ribonucleoside analogs with novel hydrogen bonding patterns

This invention relates to nucleoside, nucleotide, and oligonucleotide analogs that incorporate non-standard nucleobase analogs, defined to be those that present a pattern of hydrogen bonds to a paired nucleobase analog in a complementary strand that is different from the pattern presented by adenine, guanine, cytosine, and thymine. The invention is specifically concerned with nucleotide analogs that present the donor-donor-acceptor, hydrogen bonding patterns on pyrimidine analogs, and especially those that are analogs of ribonucleotides, including protected ribonucleotides suitable for phosphoramidite-based synthesis of RNA. The heterocycles on these nucleoside analogs are aminopyridones that have electron withdrawing groups attached to the position analogous to the 5-position of the ring in standard pyrimidines, including nitro, cyano, and carboxylic acid derivatives.

Synthesis of 4-amino-6-chloro-1,3,5-triazin-2(1H)-ones

Conditions for selective substitution for one chlorine atom in 2-(R,R-amino)-4,6-dichloro-1,3,5-triazines with a hydroxide ion were elaborated. Spectral and calculation methods showed that the products formed are in the lactam form, i.e., have the structure of 4-chloro-6-(R,R- amino)-1,3,5-triazin-2(1H)-ones.

Broad-spectrum inhibitor of viruses in the Flaviviridae family

The present invention relates generally to the fields of chemistry and molecular biology. More particularly, it concerns the use of compounds to treat viral infection. In a preferred embodiment, 2-amino-8-(β-D-ribofuranosyl) imidazo [1,2-a]-s-triazine-4-o

Imidazo[1,2-a]-s-triazine

Imidazo[1,2-a]-s-triazines including the base, the nucleoside, derivatives of the nucleoside, and the 5' nucleotide are prepared and are useful as antiviral Agents against RNA viruses.