38877-33-7

Upstream product

• 6205-69-2 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl azide 
• 129835-74-1 Z-Asnβ-(Ac3GlcNAc)α-OBu^t 
• 202266-03-3 bis(2-methoxyethyl) N-benzyloxycarbonyl-L-aspartate 
• 202266-07-7 N-benzyloxycarbonyl-L-aspartic acid α-(2-methoxyethyl) ester 
• 4515-24-6 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranosylamine 
• 202266-11-3 (S)-2-Benzyloxycarbonylamino-N-((2R,3R,4R,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-3-acetylamino-tetrahydro-pyran-2-yl)-succinamic acid 2-methoxy-ethyl ester 

Downstream Products

• 129835-75-2 Z-Asnβ-(Ac3GlcNAc)LeuThrNH2 
• 129835-77-4 C6H5C(O)-Asnβ-(Ac3GlcNAc)LeuThrNH2 
• 129835-72-9 2-acetamido-1-N-<(N'-benzoylaspartylleucylthreoninamid)-4.1-yl>-2-deoxy-β-D-glucopyranosylamine 

Relevant academic research and scientific papers

Comparative lipase-catalyzed hydrolysis of ethylene glycol derived esters. The 2-methoxyethyl ester as a protective group in peptide and glycopeptide synthesis

Comparison of the lipase-catalyzed cleavage of polar esters derived from ethylene glycol proved 2-methoxyethyl (ME) esters most favorable protecting groups for the carboxylic function of peptides and glycopeptides. They combine high substrate acceptance and iligh yields of hydrolysis with favorable physicochemical properties and advantageous solubility. The application of this polar ester as protecting group was extended to N-glycosylated amino acids and N-glycopeptides. The selective removal of ME esters by lipases was achieved under mild conditions (pH 7.0 and 37°C), leaving all other linkages including peptide bonds and other ester protecting groups unaffected.

Yeast Oligosaccharyltransferase: Glycosylation of Peptide Substrates and Chemical Characterization of the Glycopeptide Product

The product of the reaction catalyzed by yeast oligosaccharyltransferase was examined in order to determine the nature of the chemical linkage between the sugar and peptide.Biosynthetic donor lipid oligosaccharide was prepared and used as a substrate