3888-22-0

Basic information

• Product Name: 4-[(4-hydroxy-3-methoxy-phenyl)methyl]-2-methoxy-phenol
• CAS NO: 3888-22-0
• Molecular Formula: C₁₅H₁₆O₄
• Molecular Weight: 260.29
• Mol File: 3888-22-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 4-[(4-hydroxy-3-methoxy-phenyl)methyl]-2-methoxy-phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(4-hydroxy-3-methoxy-phenyl)methyl]-2-methoxy-phenol(3888-22-0)
• EPA Substance Registry System: 4-[(4-hydroxy-3-methoxy-phenyl)methyl]-2-methoxy-phenol(3888-22-0)

Safety Data

• Hazardous Substances Data: 3888-22-0(Hazardous Substances Data)

Upstream product

• 498-00-0 4-hydroxymethyl-2-methoxyphenol 
• 121-33-5 vanillin 
• 50-00-0 formaldehyd 
• 90-05-1 2-methoxy-phenol 
• 7732-18-5 water 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 7368-78-7 4-bromoguaiacol 
• 63057-72-7 2-benzyloxy-5-bromoanisole 
• 60835-68-9 4-(hydroxymethyl)-2-methoxyphenyl acetate 
• 3795-82-2 2-methoxy-4-(tosylmethyl)phenol 
• 59770-86-4 (4-Hydroxy-3-methoxy-benzyl-phenyl-sulfon 
• 64-17-5 ethanol 
• 60998-35-8 4-chloromethyl-2-methoxyphenyl acetate 

Downstream Products

• 81502-73-0 6,6'-dihydroxy-5,5'-dimethoxy-3,3'-methanediyl-di-benzyl alcohol 
• 1158-27-6 bis(3,4-dimethoxyphenyl)methane 
• 32971-27-0 di(4-acetoxy-3-methoxyphenyl)methane 

Relevant articles and documents

Replacing bisphenol-A with bisguaiacol-F to synthesize polybenzoxazines for a pollution-free environment

In recent years, bisguaiacol F (BGF) is considered as a green alternative to bisphenol A (BPA). The present work deals with the synthesis of BGF and BGF-based benzoxazines, viz., bis[(3-(furan-2-yl) methyl)-3,4-dihydro-2H benzoxazin-6-yl]methane and bis[(3-octadecyl)-3,4-dihydro-2H benzoxazin-6-yl]methane, as an alternative to BPA and polybenzoxazines derived from BPA. A solventless method was adopted for the synthesis of BGF and the benzoxazine monomers. The structure and purity of BGF is confirmed by FT-IR, NMR (1H and 13C), MS and GC. The monomers were polymerized via ring opening polymerization by heating as shown by FT-IR (disappearance of the peak due to the oxazine ring at 933 cm-1). Differential scanning calorimetric (DSC) analysis of the monomers shows a wide range of processability between 77 and 122 °C. Thermal properties of the furfurylamine based polybenzoxazine (BGF-FPbz) and stearylamine based polybenzoxazine (BGF-SPbz) were investigated by thermogravimetric analysis (TGA). The results indicate that BGF-FPbz shows the maximum thermal stability when compared with BGF-SPbz. Both the polymers exhibit good flame retardant properties as shown by their LOI values (more than 26).

BISPHENOL ALTERNATIVE DERIVED FROM RENEWABLE SUBSTITUTED PHENOLICS AND THEIR INDUSTRIAL APPLICATION

A compound is provided according to structure 4, (4) wherein n has a value from 0 to 48 and Z is hydroxyl or a benzene ring bearing substituents R11-R15, wherein R1-R15 are each individually selected from the gr

Anti-inflammatory properties of quebecol and its derivatives

Herein we report our results on the anti-inflammatory activity of quebecol, a polyphenolic compound discovered in maple syrup. Bioassays demonstrated that quebecol has an anti-inflammatory effect on LPS-induced NF-κB activation and inhibits the secretion of two pro-inflammatory cytokines, IL-6 and TNF-α. We also prepared and tested precursors of quebecol and its derivatives corresponding to its substructures of interest, with the aim to study the structure-activity relationships. Comparing the results obtained for all tested compounds allowed the identification of the main moiety responsible for the anti-inflammatory activity of quebecol.