60835-68-9

Usage

Synthesis Reference(s)

Tetrahedron Letters, 27, p. 5029, 1986 DOI: 10.1016/S0040-4039(00)85125-4

Upstream product

• 881-68-5 vanillin acetate 
• 498-00-0 4-hydroxymethyl-2-methoxyphenol 
• 107866-54-6 1-acetyl-1H-1,2,3-triazolo<4,5-b>pyridine 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 108-05-4 vinyl acetate 
• 121-33-5 vanillin 

Downstream Products

• 55525-40-1 Acetic acid 4-(4-hydroxymethyl-2-methoxy-phenoxymethyl)-2-methoxy-phenyl ester 
• 958883-47-1 5-bromo-4-(hydroxymethyl)-2-methoxyphenyl acetate 
• 1000378-05-1 8-methylnonanoic acid (4-acetyloxy-3-methoxyphenyl)methyl ester 
• 1362456-68-5 4-{[(hexylcarbamoyl)oxy]methyl}-2-methoxyphenyl acetate 
• 1362456-80-1 2-methoxy-4-({[(2-methoxyethyl)carbamoyl]oxy}methyl)phenyl acetate 
• 1362456-70-9 4-{[(decylcarbamoyl)oxy]methyl}-2-methoxyphenyl acetate 
• 1362456-71-0 4-{[(heptylcarbamoyl)oxy]methyl}-2-methoxyphenyl acetate 
• 1362456-72-1 4-{[(dibutylcarbamoyl)oxy]methyl}-2-methoxyphenyl acetate 
• 1362456-73-2 4-{[(benzylcarbamoyl)oxy]methyl}-2-methoxyphenyl acetate 
• 1362456-74-3 4-{[(2-ethylhexylcarbamoyl)oxy]methyl}-2-methoxyphenyl acetate 
• 1362456-75-4 4-{[(dodecylcarbamoyl)oxy]methyl}-2-methoxyphenyl acetate 
• 1362456-76-5 N-(2-phenoxyethyl)carbamic acid [4-(acetyloxy)-3-methoxyphenyl]methyl ester 
• 1362456-77-6 N-(2-phenylethyl)carbamic acid [4-(acetoxy)-3-methoxyphenyl]methyl ester 
• 1362456-78-7 N-(cyclohexylmethyl)carbamic acid [4-(acetyloxy)-3-methoxyphenyl]methyl ester 

Relevant academic research and scientific papers

A selective and mild glycosylation method of natural phenolic alcohols

Several bioactive natural p-hydroxyphenylalkyl β-D-glucopyranosides, such as vanillyl β-D-glucopyranoside, salidroside and isoconiferin, and their glycosyl analogues were prepared by a simple reaction sequence. The highly efficient synthetic approach was achieved by utilizing acetylated glycosyl bromides as well as aromatic moieties and mild glycosylation promoters. The aglycones, p-O-acetylated arylalkyl alcohols, were prepared by the reduction of the corresponding acetylated aldehydes or acids. Various stereoselective 1,2-trans-O-glycosylation methods were studied, including the DDQ-iodine or ZnO-ZnCl2 catalyst combination. Among them, ZnO-iodine has been identified as a new glycosylation promoter and successfully applied to the stereoselective glycoside synthesis. The final products were obtained by conventional Zemplén deacetylation.

Selective acylation of the phenolic hydroxyl of (hydroxyalkyl)phenols by using vinyl carboxylates as acyl donors in the presence of rubidium fluoride

Highly selective acylation of the phenolic hydroxy group can be achieved with (hydroxyalkyl)phenols carrying both alcoholic and phenolic hydroxyls by the use of vinyl carboxylates as acyl donors in the presence of rubidium fluoride.

Pharmacologically-active vanilloid carbamates

This application relates to pharmacologically-active vanilloid compounds which are useful for the treatment of various anti-inflammatory states characterized by inhibition of FAAH, such as, Alzheimer's dementia, Parkinson's disease, depression, pain, rheu

Substituted benzyl ester derivative and use thereof

The present invention relates to a pharmaceutical composition, a food composition or a cosmetic composition, containing one or more kinds of a compound represented by the following formula (I′) wherein R1 is a hydrogen atom, a hydroxyl group, a methoxy gr

Sulfurated borohydride exchange resin: A novel reagent for selective reduction of aldehydes

Selective reduction of aldehydes is carried out by using sulfurated borohydride exchange resin as a novel reducing reagent. Other sensitive groups like F, Cl, Br, NO2, CN, OMe, ester and methylenedioxy remain intact under these reaction conditions. The isolation of pure products by simple filtration and evaporation is an important feature of this method.

An investigation of 2,4′-dihydroxy-3,3′-dimethoxy-5′-methylstilbene using X-ray crystallography and NMR spectroscopy

The E and Z forms of the title compound, C17H18O4, were examined by 13C NMR and 1H NMR spectroscopy, and the crystal structure of the E form (m.p. 397-398 K) was determined by X-ray crystallography. E

Thiadiazole derivatives for the treatment of depressive states

Thiadiazole derivatives of general formula (I) wherein R1 is selected from the class consisting of: C1-C10 linear or branched alkyl, benzyl, optionally substituted at the aromatic ring with one or more groups se

Convenient and selective acetylations of phenols, amines and alcohols

Two convenient methods have been developed for selective acetylation. In method 1, phenols and amines are selectively acetylated in the presence of alcohols by acetic anhydride in a biphasic aqueous NaOH-isopropanol mixture. In method 2, alcoholic group is acetylated in the presence of amino functions using a strong acidic resin.

SELECTIVE ACYLATIONS OF AMINOPHENOLS AND HYDROXYALKYLPHENOLS WITH 1-ACETYL-v-TRIAZOLOPYRIDINE.

The title triazolide serves as a convenient reagent for highly chemoselective acetylations of aminophenols and hydroxyalkylphenols.