389088-33-9Relevant academic research and scientific papers
BICYCLIC INHIBITORS OF ALK
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, (2012/08/07)
The present invention relates to compounds of formula (1) or pharmaceutical acceptable salts, wherein R1, X, Y, Z, A, B, G1, and n are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as ALK and methods of treating diseases such as cancer.
BICYCLIC CARBOXAMIDE INHIBITORS OF KINASES
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, (2012/08/07)
Compounds of formula (I) or pharmaceutical acceptable salts are provided, wherein X1~X5, R1~R3, A, B, Z and n are defined in the description. And compositions containing said compounds, and the uses for inhibitors of kinases such as ALK, and the uses for treating cancer thereof are provided.
Liquid-crystalline medium
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, (2008/06/13)
A liquid-crystalline medium based on a mixture of polar compounds of positive dielectric anisotropy, which comprises one or more compounds of the formula I where R1, A1, A2, Z1, Z2, L1, Ls
Discovery and optimization of a series of carbazole ureas as NPY5 antagonists for the treatment of obesity
Block, Michael H.,Boyer, Scott,Brailsford, Wayne,Brittain, David R.,Carroll, Debra,Chapman, Steve,Clarke, David S.,Donald, Craig S.,Foote, Kevin M.,Godfrey, Linda,Ladner, Anthony,Marsham, Peter R.,Masters, David J.,Mee, Christine D.,O'Donovan, Michael R.,Pease, J. Elizabeth,Pickup, Adrian G.,Rayner, John W.,Roberts, Andrew,Schofield, Paul,Suleman, Abid,Turnbull, Andrew V.
, p. 3509 - 3523 (2007/10/03)
The hypothesis that antagonists of the neuropeptide Y5 receptor would provide safe and effective appetite suppressants for the treatment of obesity has prompted vigorous research to identify suitable compounds. We discovered a series of acylated aminocarb
