38946-41-7

Basic information

• Product Name: Phenol, 2-(aminomethyl)-6-chloro-4-(1,1-dimethylethyl)-3-methoxy-, hydrochloride
• CAS NO: 38946-41-7
• Molecular Formula: C12H18ClNO2.ClH
• Molecular Weight: 280.194
• Mol File: 38946-41-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phenol, 2-(aminomethyl)-6-chloro-4-(1,1-dimethylethyl)-3-methoxy-, hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-(aminomethyl)-6-chloro-4-(1,1-dimethylethyl)-3-methoxy-, hydrochloride(38946-41-7)
• EPA Substance Registry System: Phenol, 2-(aminomethyl)-6-chloro-4-(1,1-dimethylethyl)-3-methoxy-, hydrochloride(38946-41-7)

Safety Data

• Hazardous Substances Data: 38946-41-7(Hazardous Substances Data)

Upstream product

• 38946-61-1 2-chloro-4-(1,1-dimethylethyl)-5-methoxyphenol 
• 18113-04-7 2-chloro-5-methoxy-phenol 

Downstream Products

• 63712-16-3 2-(aminomethyl)-4-(1,1-dimethylethyl)-3-methoxyphenol hydrochloride 

Relevant articles and documents

2-(Aminomethyl)phenols, a new class of saluretic agents. I. Effect of nuclear substitution

A series of 2-(aminomethyl)phenols was synthesized and tested in rats and dogs for saluretic and diuretic activity. A number of these compounds exhibit a high order of activity on iv or po administration. The most active compounds belong to a subseries of 4-alkyl-6-halo derivatives of which 2,2(aminomethyl)-4-(1,1-dimethylethyl)-6-iodophenyl, is the most active. Compound 2 also possesses significant antihypertensive activity, an adjunctive pharmacological parameter which distinguishes 2 from the other compounds prepared in this series. In addition, 2 displays both topical saluretic and antiinflammatory activities.