38956-40-0Relevant articles and documents
On water catalyst-free synthesis of benzo[: D] imidazo[2,1- b] thiazoles and novel N -alkylated 2-aminobenzo [d] oxazoles under microwave irradiation
Mukku, Narasimharao,Maiti, Barnali
, p. 770 - 778 (2020/01/23)
A highly efficient unprecedented catalyst-free microwave-assisted procedure for synthesizing benzo[d]imidazo[2,1-b]thiazoles and N-alkylated 2-aminobenzo[d]oxazol in green media was developed. The transformation provided rapid access to functionalized ben
External Oxidant-Free Regioselective Cross Dehydrogenative Coupling of 2-Arylimidazoheterocycles and Azoles with H2 Evolution via Photoredox Catalysis
Chen, Hong,Yi, Hong,Tang, Zilu,Bian, Changliang,Zhang, Heng,Lei, Aiwen
supporting information, p. 3220 - 3227 (2018/08/03)
In this work, we achieved a site-selective amination of 2-arylimidazoheterocycles on the C3 position using photo-induced external oxidant-free strategy. The C?N bond formation with H2 evolution was realized via the oxidative C?H/N?H coupling. This protocol may have significant implications in the late-modification of complicated drug molecules. In addition, we also used CV and DFT calculations to study the mechanism, which showed that the arene radical cation played an important role in accelerating the C?H amination process. (Figure presented.).
Simple and practical method for selective acylation of primary hydroxy group catalyzed by N-methyl-2-phenylimidazole (Ph-NMI) or 2-phenylimidazo[2,1-b]benzothiazoles (Ph-IBT)
Ibe, Kouta,Hasegawa, Yu-Suke,Shibuno, Misuzu,Shishido, Tsukasa,Sakai, Yuzo,Kosaki, Yu,Susa, Keisuke,Okamoto, Sentaro
, p. 7039 - 7042 (2015/01/08)
N-Methyl-2-phenylimidazole (Ph-NMI) and 2-phenylimidazo[2,1-b]benzothiazoles (Ph-IBT) catalyzed selective acylation of primary alcohols using acid anhydrides. The Ph-NMI- or Ph-IBT-catalyzed reaction using (PhCO)2O as an acylating agent could particularly acylate the primary hydroxy group of 1,n-diols (n ≥ 3) with a high, synthetically useful selectivity.