389627-87-6Relevant articles and documents
Probe for mass spectrometry of liquid sample
-
, (2008/06/13)
Disclosed is a probe for mass spectrometry of liquid samples, which may effectively ionize the sample without adding a protic solvent to the mobile phase in the ionization method in mass spectrometry of liquid samples. The probe according to the present invention has a structure represented by the Formula [I]: R2-A-R??[I](wherein R1 represents an ionic functional group which becomes an ion in a solvent, R2 represents a structure which can bind to other substance, and A represents an arbitrary spacer moiety).
2-phenylethylamine derivatives
-
, (2008/06/13)
Compounds of formula (I): STR1 or a pharmaceutically acceptable salt, ester or amide thereof, wherein: Ar is benzofuran-2-yl, or phenyl optionally substituted by groups R1 and/or R2 wherein R1 is halogen, trifluoromethyl or hydroxy and R2 is halogen; R3 is hydrogen or methyl; X is --O(CH2)a CO2 H, --O(CH2)bM or --CO2 H in which a is an integer from 1 to 6, b is an integer from 2 to 7, M is hydroxy, C1-6 alkoxy, phenyl C1-6 alkoxy, or --NR4 R5 in which R4 and R5 are each hydrogen or C1-6 alkyl or together form a five or six membered heterocyclic ring; Y is C2-6 straight or branched alkylene, with at least two carbon atoms between the --O-- and --OH; and n is 1 or 2, having anti-obesity and/or anti-hyperglycaemic activity, processes for their preparation and their pharmaceutical use.
