389633-46-9

Basic information

• Product Name: [(3aR,4S,6R,6aR)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-4-phenyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-acetaldehyde
• CAS NO: 389633-46-9
• Molecular Weight: 530.736
• Mol File: 389633-46-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [(3aR,4S,6R,6aR)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-4-phenyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-acetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: [(3aR,4S,6R,6aR)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-4-phenyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-acetaldehyde(389633-46-9)
• EPA Substance Registry System: [(3aR,4S,6R,6aR)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-4-phenyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-acetaldehyde(389633-46-9)

Safety Data

• Hazardous Substances Data: 389633-46-9(Hazardous Substances Data)

Upstream product

• 500229-14-1 (3aR,6R,6aR)-6-Hydroxymethyl-2,2-dimethyl-4-phenyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ol 
• 32257-17-3 5-Acetyl-2,3-O-isopropyliden-D-ribonolactone 
• 67814-68-0 2,3-O-isopropylidene-D-ribofuranose 
• 389633-39-0 α-(1R,5R,8R)-3,3-dimethyl-6-phenyl-6-(2'-propenyl)-8-(tert-butyldiphenylsilyloxymethyl)-2,4,7-trioxabicyclo[3.3.0]octane 
• 141979-56-8 1,5-O-diacetyl-2,3-O-isopropylidene-D-ribofuranoside 
• 174590-90-0 5-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-1-phenyl-D-ribofuranose 

Downstream Products

• 389633-42-5 (1'S,3'R,4'R,5'R,7'S)-N²-isobutyryl-7-{4'-acetoxy-1'-phenyl-3'-(tert-butyldiphenylsilyloxymethyl)-2',6'-dioxabicyclo[3.3.0]oct-7'-yl}guanine 
• 389633-44-7 (1'S,3'R,4'R,5'R,7'R)-N²-isobutyryl-7-{4'-acetoxy-1'-phenyl-3'-(tert-butyldiphenylsilyloxymethyl)-2',6'-dioxabicyclo[3.3.0]oct-7'-yl}guanine 
• 389633-41-4 (1'S,3'R,4'R,5'R,7'S)-N²-isobutyryl-9-{4'-acetoxy-1'-phenyl-3'-(tert-butyldiphenylsilyloxymethyl)-2',6'-dioxabicyclo[3.3.0]oct-7'-yl}guanine 
• 389633-43-6 (1'S,3'R,4'R,5'R,7'R)-N²-isobutyryl-9-{4'-acetoxy-1'-phenyl-3'-(tert-butyldiphenylsilyloxymethyl)-2',6'-dioxabicyclo[3.3.0]oct-7'-yl}guanine 
• 660410-57-1 (1'S,3'R,4'R,5'R,7'S)-N²-isobutyryl-9-(4'-hydroxy-3'-hydroxymethyl-1'-phenyl-2',6'-dioxabicyclo[3.3.0]oct-7'-yl)guanine 
• 389633-40-3 (1R,3R,4R,5R,7RS)-1-phenyl-3-(tert-butyldiphenylsilyloxymethyl)-4,7-diacetoxy-2,6-dioxabicylco[3.3.0]octane 
• 660410-69-5 (1'S,3'R,4'R,5'R,7'S)-N²-isobutyryl-7-(4'-hydroxy-3'-hydroxymethyl-1'-phenyl-2',6'-dioxabicyclo[3.3.0]oct-7'-yl)guanine 

Relevant articles and documents

W-shape nucleic acid (WNA) for selective formation of non-natural anti-parallel triplex including a TA interrupting site

Novel nucleoside analogs have been designed for selective formation of anti-parallel triplexes including a TA or a CG interrupting site. The new compounds are constructed of a W-shape bicyclic nucleic acid (WNA) bearing an aromatic ring as a stacking motif and a guanine for the formation of Hoogesteen hydrogen bonds, and are expected to effect triplex stabilization by both stacking and complementary hydrogen bonds. Purine-rich triplex-forming oligodeoxynucleotide (TFO) incorporating the new analog, WNA-7βG, formed a stable triplex with high selectivity to the TA site.