389860-85-9

Upstream product

• 279684-80-9 Benzoic acid (1R,2R,3S)-2-[(2S,4S,5R,6R)-4,5-bis-(tert-butyl-dimethyl-silanyloxy)-6-methyl-tetrahydro-pyran-2-yloxy]-3-(tert-butyl-dimethyl-silanyloxy)-1-methyl-pent-4-ynyl ester 
• 279684-91-2 (2R,3R,4S)-3-[(2S,4S,5R,6R)-4,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-methyl-tetrahydro-pyran-2-yloxy]-4-(tert-butyl-dimethyl-silanyloxy)-hex-5-yn-2-ol 
• 279684-92-3 4-O-[3,4-bis-(tert-butyldimethylsilyl)-2,6-dideoxy-β-D-allopyranosyl]-3-(tert-butyldimethylsilyl)-1,5-anhydro-2,6-dideoxy-D-ribo-hex-1-entol 
• 279684-79-6 (2R,3R,4S)-4-(tert-butyldimethylsiloxy)-hex-5-yne-2,3-diol 2-benzoate ester 
• 279684-76-3 3,4-bis-(tert-butyldimethylsilyl)-1,5-anhydro-2,6-dideoxy-D-ribo-hex-1-enitol 
• 389860-84-8 Acetic acid (2R,3R,4S,6S)-3-acetoxy-6-[(2R,3R,4S)-4-(tert-butyl-dimethyl-silanyloxy)-2-methyl-3,4-dihydro-2H-pyran-3-yloxy]-2-methyl-tetrahydro-pyran-4-yl ester 

Downstream Products

• 71-63-6 digitoxin 

Relevant academic research and scientific papers

Convergent synthesis of digitoxin: Stereoselective synthesis and glycosylation of the digoxin trisaccharide glycal

Tungsten-catalyzed alkynol cycloisomerization and iterative acid-catalyzed stereoselective glycosylations form the basis of a revolutionary new strategy for oligosaccharide synthesis. The method has been successfully applied to a highly convergent synthesis of Digitalis 2-deoxyglycosides.