3900-94-5

Upstream product

• 137-43-9 Cyclopentyl bromide 
• 7037-44-7 α-phenylcyclopentaneacetyl chloride 
• 140-29-4 phenylacetonitrile 
• 3900-93-4 2-cyclopentyl-2-phenylacetic acid 

Downstream Products

• 175343-28-9 2-cyclopentyl-2-phenylethan-1-amine 

Relevant academic research and scientific papers

Copper-Catalyzed Amide Radical-Directed Cyanation of Unactivated Csp3-H Bonds

A method for site-selective intermolecular δ/?-Csp3-H cyanation of aliphatic sulfonamides is developed using TsCN as the cyanating reagent, catalyzed by a Cu(I)/phenanthroline complex. The mild, expeditious, and modular protocol allows efficient remote Csp3-H cyanation with good functional group tolerance and high regioselectivity. Mechanistic studies indicate that the reaction might proceed through a Cu(I)-mediated N-F bond cleavage to generate an amidyl radical, 1,5-HAT, and cyano group transfer of the resulting carbon radical with TsCN.

ACID AND ESTER COMPOUNDS AND METHODS OF USING THE SAME

Disclosed is a compound of having the formula (II-A), pharmaceutically acceptable salts or solvates thereof and pharmaceutical compositions containing the same, wherein the structural variables are as defined herein. The compounds, salts and solvates of this invention are useful as LXR agonists.