175343-28-9

Usage

Uses

Used in Pharmaceutical Synthesis:
(2-Cyclopentyl-2-phenylethyl)amine is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs and medicinal compounds. Its unique structure allows for the creation of a wide range of therapeutic agents.
Used in Organic Compounds Synthesis:
In the field of organic chemistry, (2-Cyclopentyl-2-phenylethyl)amine is used as an intermediate for the synthesis of various organic compounds, leveraging its cyclopentyl and phenylethyl groups to form complex molecules with specific properties.
Used in Research and Development:
(2-Cyclopentyl-2-phenylethyl)amine is utilized in research and development settings to explore its potential biological activity and applications. This may include studies on its interactions with biological systems and its use in creating new chemical entities with therapeutic or other beneficial properties.
Depending on the specific application and industry, (2-Cyclopentyl-2-phenylethyl)amine may have additional uses that are tailored to the needs of that particular field. Its properties and versatility make it a valuable compound in the ongoing pursuit of scientific and medical advancements.

InChI:InChI=1/C13H19N/c14-10-13(12-8-4-5-9-12)11-6-2-1-3-7-11/h1-3,6-7,12-13H,4-5,8-10,14H2

Upstream product

• 75366-33-5 1-cyclopentyl-1-phenylethene 
• 3900-94-5 cyclopentyl-phenyl-acetic acid amide 
• 7037-44-7 α-phenylcyclopentaneacetyl chloride 
• 3900-93-4 2-cyclopentyl-2-phenylacetic acid 

Downstream Products

• 610319-20-5 N-(2-phenyl-2-cyclopentylethyl)-2-chloro-3-trifluoromethylbenzylamine 

Relevant academic research and scientific papers

Direct Access to Primary Amines from Alkenes by Selective Metal-Free Hydroamination

Direct and selective synthesis of primary amines from easily available precursors is attractive yet challenging. Herein, we report the rapid synthesis of primary amines from alkenes via metal-free regioselective hydroamination at room temperature. Ammonium carbonate was used as ammonia surrogate for the first time, allowing for efficient conversion of terminal and internal alkenes into linear, α-branched, and α-tertiary primary amines under mild conditions. This method provides a straightforward and powerful approach to a wide spectrum of advanced, highly functionalized primary amines which are of particular interest in pharmaceutical chemistry and other areas.

Copper-Catalyzed Amide Radical-Directed Cyanation of Unactivated Csp3-H Bonds

A method for site-selective intermolecular δ/?-Csp3-H cyanation of aliphatic sulfonamides is developed using TsCN as the cyanating reagent, catalyzed by a Cu(I)/phenanthroline complex. The mild, expeditious, and modular protocol allows efficient remote Csp3-H cyanation with good functional group tolerance and high regioselectivity. Mechanistic studies indicate that the reaction might proceed through a Cu(I)-mediated N-F bond cleavage to generate an amidyl radical, 1,5-HAT, and cyano group transfer of the resulting carbon radical with TsCN.

ACID AND ESTER COMPOUNDS AND METHODS OF USING THE SAME

Disclosed is a compound of having the formula (II-A), pharmaceutically acceptable salts or solvates thereof and pharmaceutical compositions containing the same, wherein the structural variables are as defined herein. The compounds, salts and solvates of this invention are useful as LXR agonists.

β-carboxy sulfonamide ACAT inhibitors

β-Carboxy sulfonyl compounds of the formula STR1 wherein R1 is aryl, R3 is hydrogen or alkyl, R3 and R4 are hydrogen or alkyl, Y is --O--, --S--, or --NR2 --, and R5 is alkyl or aryl are potent inhibitors of the enzyme acyl CoA:cholesterol acyltransferase (ACAT) and are thus useful for treating hypercholesterolemia and atherosclerosis.