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(8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine hydrochloride is a chemical compound with the molecular formula C15H22ClNO. It is a derivative of naphthalene, a type of aromatic hydrocarbon, and features a propylamine group attached to the naphthalene structure. The compound is characterized by the presence of a methoxy group at the 8-position, which contributes to its unique chemical properties. This substance is often used in the synthesis of various pharmaceuticals and organic compounds due to its versatile structure and reactivity. It is typically obtained as a hydrochloride salt, which enhances its solubility in water and facilitates its use in various chemical reactions.

3902-22-5

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3902-22-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3902-22-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,9,0 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 3902-22:
(6*3)+(5*9)+(4*0)+(3*2)+(2*2)+(1*2)=75
75 % 10 = 5
So 3902-22-5 is a valid CAS Registry Number.

3902-22-5Relevant academic research and scientific papers

Synthesis of Pharmaceutically Relevant 2-Aminotetralin and 3-Aminochroman Derivatives via Enzymatic Reductive Amination

Citoler, Joan,Harawa, Vanessa,Marshall, James R.,Bevinakatti, Han,Finnigan, James D.,Charnock, Simon J.,Turner, Nicholas J.

supporting information, p. 24456 - 24460 (2021/10/19)

2-Aminotetralin and 3-aminochroman derivatives are key structural motifs present in a wide range of pharmaceutically important molecules. Herein, we report an effective biocatalytic approach towards these molecules through the enantioselective reductive coupling of 2-tetralones and 3-chromanones with a diverse range of primary amine partners. Metagenomic imine reductases (IREDs) were employed as the biocatalysts, obtaining high yields and enantiocomplementary selectivity for >15 examples at preparative scale, including the precursors to Ebalzotan, Robalzotan, Alnespirone and 5-OH-DPAT. We also present a convergent chemo-enzymatic total synthesis of the Parkinson's disease therapy Rotigotine in 63 % overall yield and 92 % ee.

NEW AMINOTETRALINE DERIVATIVES

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Page/Page column 31-32, (2011/07/09)

The present application relates to compounds of formula (I): and pharmaceutically acceptable salts and solvates thereof, wherein the substituents are as defined herein, compositions containing such compounds and the uses of such compounds in producing med

METHOD OF INHIBITING GASTRIC ACID SECRETION

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, (2008/06/13)

The present invention provides a method of inhibiting gastric acid secretion in mammals by administering a 5-HT1A agonist compound or a pharmaceutically acceptable salt thereof.

METHOD OF INHIBITING GASTRIC ACID SECRETION WITH BENZODIOXANES

-

, (2008/06/13)

The present invention provides a method of inhibiting gastric acid secretion in mammals by administering a 5-HT1A agonist compound or a pharmaceutically acceptable salt thereof.

2-(Alkylamino)tetralin Derivatives: Interaction with 5-HT1A Serotonin Binding Sites

Naiman, Noreen,Lyon, Robert A.,Bullock, Amy E.,Rydelek, Laura T.,Titeler, Milt,Glennon, Richard A.

, p. 253 - 256 (2007/10/02)

8-Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) is a selective 5-HT1A serotonin agonist.Derivatives of 8-OH-DPAT with amine substituents larger or more bulky than n-propyl appear to be inactive in a presynaptic biochemical assay measuring ag

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