39053-40-2

Usage

Uses

Used in Pharmaceutical Industry:
3-NITRO-2-METHYL-BENZYLBROMIDE is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 3-NITRO-2-METHYL-BENZYLBROMIDE is employed as an intermediate in the production of agrochemicals, contributing to the creation of compounds that can enhance crop protection and yield.
Used in Organic Synthesis:
3-NITRO-2-METHYL-BENZYLBROMIDE is utilized as a reagent in organic synthesis for the construction of a wide range of organic molecules. Its brominated benzyl structure provides a versatile platform for further chemical reactions and modifications, facilitating the synthesis of complex organic compounds.
Safety Considerations:
As a brominated benzyl compound, it is crucial to handle 3-NITRO-2-METHYL-BENZYLBROMIDE with care and adhere to proper safety protocols when working with this chemical to ensure the safety of personnel and the environment.

Upstream product

• 83-41-0 2,3-dimethylnitrobenzene 
• 23876-13-3 (2-methyl-3-nitrophenyl)methanol 

Downstream Products

• 928128-10-3 methyl 3-[(5-formyl-2,6-dichloropyrimidin-4-yl)methylamino]-2-methylbenzenepropanoate 
• 928128-07-8 dimethyl 2-[(2-methyl-3-nitrophenyl)methyl]propanedionate 
• 1192039-91-0 tert-butyl 1-(2-methyl-3-nitrobenzyl)cyclopropanecarboxylate 
• 1192039-92-1 tert-butyl 1-(3-amino-2-methylbenzyl)cyclopropanecarboxylate 
• 928128-14-7 pentafluorophenyl 2,3,4,10-tetrahydro-9,10-dimethyl-2,4-dioxo-3-[2-oxo-2-(pentafluorophenoxy)ethyl]pyrimido[4,5-b]quinoline-8-propanoate 
• 928128-06-7 methyl 2-methyl-3-(methylamino)benzenepropanoate 
• 928128-08-9 methyl 2-methyl-3-nitrobenzenepropanoate 
• 928128-09-0 methyl 3-amino-2-methylbenzenepropanoate 
• 6551-36-6 4-(2-methyl-3-nitro-benzyl)-morpholine 

Relevant academic research and scientific papers

METHOD FOR PRODUCING 2-(HALOGENOMETHYL)-3-METHYLNITROBENZENE

Position-1 halogen can be selectively reduced by reacting a compound represented by formula (3): [wherein X represents a chlorine atom, a bromine atom, or an iodine atom] with halogen in the presence of a heterogeneous transition metal catalyst to produce 2-(halogenomethyl)-1-methyl-3-nitrobenzene represented by formula (1): [wherein the symbol is as defined above].

Synthesis and photophysical properties of a deazaflavin-bridged porphyrinatoiron(III) that mimics the interaction of a deazaflavin inhibitor with the heme-thiolate cofactor of cytochrome P450 3A4

Cytochrome P450 3A4 metabolizes a majority of administered therapeutic agents in the human liver. We recently reported the synthesis of a new inhibitor, 1, whose binding to and displacement from the active site of CYP 3A4 can be conveniently followed by t

SPECIFIC ORTHO ORIENTATION IN THE VICARIOUS SUBSTITUTION OF HYDROGEN IN AROMATIC NITRO COMPOUNDS WITH CARBANION OF CHLOROMETHYL PHENYL SULFONE

Vicarious nucleophilic substitution of hydrogen atoms in nitroarenes with chloromethylphenyl sulfone proceeds selectively ortho to the nitro group when carried out in t-BuOK/THF base/solvent system.In the majority of 3-substituted nitrobenzene derivatives substitution occurs at the most hindered position 2.These conditions offer an efficient method of synthesis of 2,6 and 2,3-disubstituted nitrobenzene derivatives.