39057-67-5Relevant academic research and scientific papers
Sustainable Access to 5-Amino-Oxazoles and Thiazoles via Calcium-Catalyzed Elimination-Cyclization with Isocyanides
Basson, Ashley J.,McLaughlin, Mark G.
, p. 1696 - 1699 (2021/03/08)
Herein, we report a sustainable, modular, rapid and high-yielding transformation to afford densely functionalized 5-aminooxazoles and thiazoles. The reaction is tolerant to a wide range of functional groups and is typically complete in under 30 min. Furth
4+1 Cycloaddition of N-acylimine derivatives with isocyanides: Efficient synthesis of 5-aminooxazoles and 5-aminothiazoles
Soeta, Takahiro,Tamura, Kaname,Ukaji, Yutaka
supporting information, p. 3005 - 3010 (2014/04/17)
[4+1] Cycloaddition reaction between isocyanides and N-acylimine derivatives generated from N-acyl N,O-acetals acting as isocyanophiles has been developed. These reactions proceeded smoothly and cleanly to afford the corresponding 5-aminooxazoles in high
