390824-34-7

Upstream product

• 390824-26-7 methyl 3-O-benzyl-β-L-ribofuranoside 
• 206269-25-2 methyl 2,3,5-tri-O-acetyl-β-L-ribofuranoside 
• 390824-25-6 1,5-di-O-acetyl-3-O-benzyl-2-O-methanesulfonyl-L-arabinofuranose 
• 659722-56-2 methyl 2,3,5-tri-O-acetyl-β/α-L-ribofuranoside 
• 52689-56-2 methyl β-L-ribofuranoside 
• 176299-71-1 1,2,3,5-tetraacetyl-L-ribofuranose 
• 4005-49-6 N-benzoyladenine 
• 144490-03-9 1,2,3,5-tetra-O-acetyl-β-L-ribofuranose 

Downstream Products

• 770728-13-7 6-N-benzoyl-9-[5',6'-dideoxy-2',3'-O-isopropylidene-6'-(p-toluenesulfonyl)-β-L-ribo-hex-5'(E)-enofuranosyl] adenosine 
• 770728-14-8 N-(9-{2,2-dimethyl-6-[2-(toluene-4-sulfonyl)-ethylidene]-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl}-9H-purin-6-yl)-benzamide 
• 770728-22-8 6-N-benzoyl-9-[5'-deoxy-5'-iodo-2',3'-O-isopropylidene-β-L-ribo-hex-5'(E)-enofuranosyl] adenosine 
• 868663-26-7 N⁶-benzoyl-β-L-adenosine 
• 58-61-7 L-adenosine 

Relevant academic research and scientific papers

Synthesis and biological activities of 5′-ethylenic and acetylenic modified L-nucleosides and isonucleosides

Two series of 6′-halovinyl-adenosine stereoisomers including 5′-ethylenic and acetylenic substituted l-adenosine, 5′-ethylenic and acetylenic substituted isonucleosides were synthesized. In the l-nucleoside series, compounds 6b, 8b, 10b and 13b showed mod

A stereospecific synthesis of L-deoxyribose, L-ribose and L-ribosides

Using an inexpensive D-galactose from the chiral pool, L-deoxyribose, L-ribose and their derivatives were synthesized via mild reaction conditions. During the synthesis of L-deoxyribose, the key deoxygenation of the 2-hydroxy group of 3,5-O-dibenzyl-methyl-L-arabinofuranoside was performed by reduction of the corresponding triflate with tetrabutylammonium borohydride in high yield. During the synthesis of L-ribose, the key step of inversion of the 2-hydroxy group in the same substrate was carried out by intramolecular SN2 tandem reaction. Then the L-ribosyl donors were submitted to glycosidations according to Vorbrüggen's conditions to give L-ribosides (L-uridine, L-5-fluorouridine, L-iodouridine, L-thymidine, L-puridine, L-adenosine and L-guanosine) in excellent yields.

A stereospecific synthesis of L-ribose and L-ribosides from D-galactose

An inexpensive D-galactose was converted into L-ribose and its derivatives via mild reaction conditions. The L-ribosyl donor was submitted to a glycosidation according to Vorbrüggen's conditions to give L-ribosides in high yields.