39089-30-0 Usage
Uses
Used in Pharmaceutical Industry:
Karakoline is used as a neurotoxin for its ability to activate tetrodotoxin-sensitive Na+ channels. This activation induces presynaptic depolarization, which in turn blocks the nerve action potential. By blocking the nerve action potential, karakoline inhibits the release of neurotransmitters and decreases the end plate potential at the neuromuscular junction. This unique mechanism of action makes it a potential candidate for various pharmaceutical applications, particularly in the development of drugs targeting the nervous system.
References
Sultankhodzhaev, Yunusov, Yunusov., Khim. Prir. Soedin., 9, 199 (1973)
Check Digit Verification of cas no
The CAS Registry Mumber 39089-30-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,0,8 and 9 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 39089-30:
(7*3)+(6*9)+(5*0)+(4*8)+(3*9)+(2*3)+(1*0)=140
140 % 10 = 0
So 39089-30-0 is a valid CAS Registry Number.
InChI:InChI=1/C22H35NO4/c1-4-23-10-20(2)6-5-16(24)22-12-7-11-14(27-3)9-21(26,17(12)18(11)25)13(19(22)23)8-15(20)22/h11-19,24-26H,4-10H2,1-3H3/t11-,12-,13+,14+,15-,16+,17-,18+,19?,20+,21+,22-/m1/s1