39101-99-0

Basic information

• Product Name: 2-amino-3-(3,4-diacetoxyphenyl)-propionic acid
• CAS NO: 39101-99-0
• Molecular Weight: 295.292
• Mol File: 39101-99-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-amino-3-(3,4-diacetoxyphenyl)-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-3-(3,4-diacetoxyphenyl)-propionic acid(39101-99-0)
• EPA Substance Registry System: 2-amino-3-(3,4-diacetoxyphenyl)-propionic acid(39101-99-0)

Safety Data

• Hazardous Substances Data: 39101-99-0(Hazardous Substances Data)

Upstream product

• 59-92-7 levodopa 
• 7101-51-1 L-DOPA methyl ester 
• 75-36-5 acetyl chloride 

Relevant articles and documents

Design and synthesis of a novel L-Dopa - Entacapone codrug

A novel codrug, in which L-Dopa and entacapone are linked via a biodegradable carbamate spacer to form a single chemical entity, was synthesized and studied kinetically. This carbamate codrug provides adequate stability [t1/2 = 12.1 h (pH 1.2); 1.4 h (pH 5.0); 1.1 h (pH 7.4)] against chemical hydrolysis but rapidly hydrolyzes to L-Dopa and entacapone in liver homogenate (t1/2 = 7 min; pH 7.4) at 37°C. The therapeutical potential of this novel codrug is discussed.