391213-72-2

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 586413-60-7 diphenylmethylamino-p-methoxy-m-(tert-butyldimethylsilyloxy)phenylacetonitryle 
• 1027416-60-9 [1-(3-benzyloxy-4-methoxy-phenyl)-2-hydroxy-ethyl]-carbamic acid tert-butyl ester 
• 6346-05-0 3-benzyloxy-4-methoxybenzaldehyde 
• 73210-14-7 N-chloro-N-sodio-tert-butylcarbamate 
• 68360-39-4 2-(3-benzyloxy-4-methoxyphenyl)ethylene 
• 586413-59-4 p-methoxy-m-(tert-butyldimethylsilyloxy)-benzaldehyde diphenylmethyl imine 
• 97315-18-9 p-methoxy-m-(tert-butyldimethylsilyloxy)-benzaldehyde 

Downstream Products

• 391213-74-4 (R)-2-[(R)-2-tert-Butoxycarbonylamino-2-(3-hydroxy-4-methoxy-phenyl)-acetylamino]-3-(4-fluoro-3-nitro-phenyl)-propionic acid methyl ester 
• 391213-78-8 (R)-2-[(R)-2-{3-[3-((S)-tert-Butoxycarbonylamino-methylcarbamoyl-methyl)-5-methoxy-phenoxy]-4-methoxy-phenyl}-2-(2,2,2-trifluoro-acetylamino)-acetylamino]-3-(4-fluoro-3-nitro-phenyl)-propionic acid methyl ester 
• 391213-80-2 (R)-2-[(R)-2-{3-[3-((S)-tert-Butoxycarbonylamino-methylcarbamoyl-methyl)-5-methoxy-phenoxy]-4-methoxy-phenyl}-2-(2,2,2-trifluoro-acetylamino)-acetylamino]-3-(4-fluoro-3-nitro-phenyl)-propionic acid 
• 391213-82-4 (8S,11R,14R)-11-(4-Fluoro-3-nitro-benzyl)-5,18-dimethoxy-10,13-dioxo-14-(2,2,2-trifluoro-acetylamino)-2-oxa-9,12-diaza-tricyclo[13.3.1.1^3,7]icosa-1⁽¹⁸⁾,3⁽²⁰⁾,4,6,15⁽¹⁹⁾,16-hexaene-8-carboxylic acid methylamide 
• 391213-84-6 (8S,11R,14R)-11-(4-Fluoro-3-nitro-benzyl)-5,18-dimethoxy-10,13-dioxo-14-(2,2,2-trifluoro-acetylamino)-2-oxa-9,12-diaza-tricyclo[13.3.1.1^3,7]icosa-1⁽¹⁸⁾,3⁽²⁰⁾,4,6,15⁽¹⁹⁾,16-hexaene-8-carboxylic acid 
• 391213-76-6 (R)-3-(4-Fluoro-3-nitro-phenyl)-2-[(R)-2-(3-hydroxy-4-methoxy-phenyl)-2-(2,2,2-trifluoro-acetylamino)-acetylamino]-propionic acid methyl ester 
• 586413-58-3 C₅₉H₅₃Cl₄N₇O₁₄ 
• 586413-55-0 C₄₈H₄₄Cl₄IN₅O₁₃ 
• 586413-71-0 C₄₃H₄₄Cl₂F₃IN₄O₁₀Si 
• 586413-54-9 C₄₃H₄₅Cl₂F₃N₄O₁₀Si 
• 586413-72-1 (R)-{[(8R,11R,14S)-8-Amino-11-(3,5-dichloro-4-hydroxy-phenyl)-4-hydroxy-5-iodo-13-methyl-9,12-dioxo-2-oxa-10,13-diaza-tricyclo[14.2.2.1^3,7]henicosa-1⁽¹⁹⁾,3⁽²¹⁾,4,6,16⁽²⁰⁾,17-hexaene-14-carbonyl]-amino}-(4-hydroxy-phenyl)-acetic acid methyl ester 
• 586413-70-9 (8R,11R,14S)-11-(3,5-Dichloro-4-hydroxy-phenyl)-4-hydroxy-13-methyl-9,12-dioxo-8-(2,2,2-trifluoro-acetylamino)-2-oxa-10,13-diaza-tricyclo[14.2.2.1^3,7]henicosa-1⁽¹⁹⁾,3⁽²¹⁾,4,6,16⁽²⁰⁾,17-hexaene-14-carboxylic acid 
• 586413-69-6 (8R,11R,14S)-11-(3,5-Dichloro-4-methoxy-phenyl)-4-methoxy-13-methyl-9,12-dioxo-8-(2,2,2-trifluoro-acetylamino)-2-oxa-10,13-diaza-tricyclo[14.2.2.1^3,7]henicosa-1⁽¹⁹⁾,3⁽²¹⁾,4,6,16⁽²⁰⁾,17-hexaene-14-carboxylic acid methyl ester 
• 586413-52-7 (8R,11R,14S)-8-tert-Butoxycarbonylamino-11-(3,5-dichloro-4-methoxy-phenyl)-4-methoxy-13-methyl-9,12-dioxo-2-oxa-10,13-diaza-tricyclo[14.2.2.1^3,7]henicosa-1⁽¹⁹⁾,3⁽²¹⁾,4,6,16⁽²⁰⁾,17-hexaene-14-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Total synthesis of anti-HIV agent chloropeptin I

A convergent diastereo- and enantioselective total synthesis of anti-HIV agent chloropeptin I is reported. Important features of the total synthesis include: (1) the use of Ti-catalyzed cyanide addition to imines to prepare a requisite amino acid moiety,