586413-72-1

Upstream product

• 586413-71-0 C₄₃H₄₄Cl₂F₃IN₄O₁₀Si 
• 1042907-20-9 C₄₀H₃₉Cl₂IN₄O₁₁ 
• 586413-54-9 C₄₃H₄₅Cl₂F₃N₄O₁₀Si 
• 586413-51-6 (S)-2-{[(R)-2-[(R)-2-tert-Butoxycarbonylamino-2-(3-hydroxy-4-methoxy-phenyl)-acetylamino]-2-(3,5-dichloro-4-methoxy-phenyl)-acetyl]-methyl-amino}-3-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-propionic acid methyl ester 
• 586413-70-9 (8R,11R,14S)-11-(3,5-Dichloro-4-hydroxy-phenyl)-4-hydroxy-13-methyl-9,12-dioxo-8-(2,2,2-trifluoro-acetylamino)-2-oxa-10,13-diaza-tricyclo[14.2.2.1^3,7]henicosa-1⁽¹⁹⁾,3⁽²¹⁾,4,6,16⁽²⁰⁾,17-hexaene-14-carboxylic acid 
• 586413-69-6 (8R,11R,14S)-11-(3,5-Dichloro-4-methoxy-phenyl)-4-methoxy-13-methyl-9,12-dioxo-8-(2,2,2-trifluoro-acetylamino)-2-oxa-10,13-diaza-tricyclo[14.2.2.1^3,7]henicosa-1⁽¹⁹⁾,3⁽²¹⁾,4,6,16⁽²⁰⁾,17-hexaene-14-carboxylic acid methyl ester 
• 586413-52-7 (8R,11R,14S)-8-tert-Butoxycarbonylamino-11-(3,5-dichloro-4-methoxy-phenyl)-4-methoxy-13-methyl-9,12-dioxo-2-oxa-10,13-diaza-tricyclo[14.2.2.1^3,7]henicosa-1⁽¹⁹⁾,3⁽²¹⁾,4,6,16⁽²⁰⁾,17-hexaene-14-carboxylic acid methyl ester 
• 586413-49-2 (S)-2-{[(R)-2-tert-Butoxycarbonylamino-2-(3,5-dichloro-4-methoxy-phenyl)-acetyl]-methyl-amino}-3-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-propionic acid methyl ester 
• 586413-68-5 (8R,11R,14S)-8-Amino-11-(3,5-dichloro-4-methoxy-phenyl)-4-methoxy-13-methyl-9,12-dioxo-2-oxa-10,13-diaza-tricyclo[14.2.2.1^3,7]henicosa-1⁽¹⁹⁾,3⁽²¹⁾,4,6,16⁽²⁰⁾,17-hexaene-14-carboxylic acid methyl ester 
• 586413-60-7 diphenylmethylamino-p-methoxy-m-(tert-butyldimethylsilyloxy)phenylacetonitryle 
• 586413-59-4 p-methoxy-m-(tert-butyldimethylsilyloxy)-benzaldehyde diphenylmethyl imine 
• 586413-61-8 (R)-N-(t-butoxycarbonyl)-4-(t-butyldimethylsiloxy)phenylglycine methyl ester 
• 586413-53-8 amino-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-acetic acid methyl ester 
• 391213-72-2 (R)-N-Boc-m-hydroxy-p-methoxyphenyl-Gly 

Downstream Products

• 586413-55-0 C₄₈H₄₄Cl₄IN₅O₁₃ 
• 586413-58-3 C₅₉H₅₃Cl₄N₇O₁₄ 

Relevant academic research and scientific papers

Synthesis of diastereomers of complestatin and chloropeptin I: Substrate-dependent atropstereoselectivity of the intramolecular Suzuki-Miyaura reaction

See the effect of C: Atropisomers as well as CC2 epimers of complestatin and chloropeptin I (see picture) are readily synthesized through an intramolecular SNAr reaction and the Suzuki-Miyaura reaction. The absolute configuration of

Total synthesis of anti-HIV agent chloropeptin I

A convergent diastereo- and enantioselective total synthesis of anti-HIV agent chloropeptin I is reported. Important features of the total synthesis include: (1) the use of Ti-catalyzed cyanide addition to imines to prepare a requisite amino acid moiety,