391248-23-0

Basic information

• Product Name: ETHYL 2-(4'-BROMOPHENYL)-1,3-OXAZOLE-4-CARBOXYLATE
• Synonyms: ETHYL 2-(4'-BROMOPHENYL)-1,3-OXAZOLE-4-CARBOXYLATE;2-(4-BROMO-PHENYL)-OXAZOLE-4-CARBOXYLIC ACID ETHYL ESTER;ethyl 2-(4-bromophenyl)oxazole-4-carboxylate;4-Oxazolecarboxylic acid, 2-(4-bromophenyl)-, ethyl ester;Ethyl 2-(4-bromophenyl)-1,3-
• CAS NO: 391248-23-0
• Molecular Formula: C₁₂H₁₀BrNO₃
• Molecular Weight: 296.12
• Mol File: 391248-23-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 380.9 °C at 760 mmHg
• Flash Point: 184.1 °C
• Appearance: /
• Density: 1.471 g/cm³
• Vapor Pressure: 5.28E-06mmHg at 25°C
• Refractive Index: 1.562
• Storage Temp.: 2-8°C
• CAS DataBase Reference: ETHYL 2-(4'-BROMOPHENYL)-1,3-OXAZOLE-4-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-(4'-BROMOPHENYL)-1,3-OXAZOLE-4-CARBOXYLATE(391248-23-0)
• EPA Substance Registry System: ETHYL 2-(4'-BROMOPHENYL)-1,3-OXAZOLE-4-CARBOXYLATE(391248-23-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 391248-23-0(Hazardous Substances Data)

Usage

General Description

Ethyl 2-(4'-Bromophenyl)-1,3-oxazole-4-carboxylate is a complex chemical compound. It has a bromine atom which makes it an organobromine compound, a common type of organohalogen compound. This chemical also contains a phenyl ring attached to an oxazole ring, increasing its structural complexity. The oxazole ring is a heterocyclic compound containing an atom of nitrogen and an atom of oxygen. The presence of a carboxylate group, a derivative of carboxylic acid, further diversifies its chemical structure. ETHYL 2-(4'-BROMOPHENYL)-1,3-OXAZOLE-4-CARBOXYLATE can be used in a variety of chemical reactions due to its intricate structure, but its specific uses would depend on the particular chemical reactions it undergoes.

InChI:InChI=1/C12H10BrNO3/c1-2-16-12(15)10-7-17-11(14-10)8-3-5-9(13)6-4-8/h3-7H,2H2,1H3

Upstream product

• 70-23-5 ethyl Bromopyruvate 
• 698-67-9 p-bromobenzamide 
• 23012-14-8 oxazole-4-carboxylic acid ethyl ester 
• 589-87-7 1,4-bromoiodobenzene 

Downstream Products

• 1582221-33-7 ethyl 2-(4-bromophenyl)-5-phenyloxazole-4-carboxylate 

Relevant articles and documents

Synthesis and bioactivity of phenyl substituted furan and oxazole carboxylic acid derivatives as potential PDE4 inhibitors

In this present study, a series of 5-phenyl-2-furan and 4-phenyl-2-oxazole derivatives were designed and synthesized as phosphodiesterase type 4 (PDE4) inhibitors. In vitro results showed that the synthesized compounds exhibited considerable inhibitory ac

Design, synthesis and biological evaluation of 2,4-disubstituted oxazole derivatives as potential PDE4 inhibitors

In this study, a series of pyrazole derivatives containing 4-phenyl-2-oxazole moiety were designed and synthesized in a concise way, some of which exhibited considerable inhibitory activity against PDE4B and blockade of LPS-induced TNF-α release. Compound

A silver-mediated one-step synthesis of oxazoles

A silver-mediated one-step procedure to 2,4-disubstituted and 2,4,5-trisubstituted oxazoles has been developed. The method is complementary to existing technologies, yet provides advantages with regard to simplicity, efficiency, and performance. The silver product can be readily recycled, thus minimizing waste.