23012-14-8

Basic information

• Product Name: Ethyl oxazole-4-carboxylate
• Synonyms: ETHYL OXAZOLE-4-CARBOXYLATE;ETHYL 4-OXAZOLECARBOXYLATE;4-OXAZOLECARBOXYLIC ACID ETHYL ESTER;OXAZOLE-4-CARBOXYLIC ACID ETHYL ESTER;Ethyl 1,3-oxazole-4-carboxylate;Ethyl 1,3-oxazole-4-carboxylate 97%;4-Oxazolecarboxylicacid,ethylester(8CI,9CI);4-(Ethoxycarbonyl)-1,3-oxazole
• CAS NO: 23012-14-8
• Molecular Formula: C₆H₇NO₃
• Molecular Weight: 141.12
• Product Categories: CARBOXYLICESTER;blocks;Oxazoles;Building Blocks;Oxazole
• Mol File: 23012-14-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 48°C
• Boiling Point: 101°C 14mm
• Flash Point: 75.9 °C
• Appearance: /
• Density: 1.177 g/mL at 25 °C
• Refractive Index: n20/D 1.467
• Storage Temp.: Refrigerator
• PKA: -1?+-.0.10(Predicted)
• CAS DataBase Reference: Ethyl oxazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl oxazole-4-carboxylate(23012-14-8)
• EPA Substance Registry System: Ethyl oxazole-4-carboxylate(23012-14-8)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 23012-14-8(Hazardous Substances Data)

Usage

General Description

Ethyl oxazole-4-carboxylate is a chemical compound with the molecular formula C7H7NO3. It is a derivative of oxazole, a heterocyclic aromatic organic compound. Ethyl oxazole-4-carboxylate has been studied for its potential use in pharmaceuticals and as a building block in organic synthesis. It is often used as a key intermediate in the production of various drugs and agricultural chemicals. Ethyl oxazole-4-carboxylate is known for its wide range of applications in medical and agricultural industries, and its unique chemical properties make it a valuable component in the development of diverse products.

Upstream product

• 123-91-1 1,4-dioxane 
• 247940-06-3 CyJohnPhos 
• 177760-52-0 ethyl 2-aminooxazole-4-carboxylate 
• 10535-67-8 trimethylacetic formic anhydride 
• 2999-46-4 Ethyl isocyanoacetate 
• 2949-22-6 Glycine ethyl ester isocyanate 
• 3154-51-6 ethyl N-formylglycinate 
• 530-62-1 1,1'-carbonyldiimidazole 
• 64-18-6 formic acid 

Downstream Products

• 23012-15-9 oxazol-4-carboxamide 
• 23012-13-7 1,3-oxazole-4-carboxylic acid 
• 460081-24-7 2-vinyloxazole-4-carboxylic acid ethyl ester 
• 885274-12-4 4-oxazolecarboxylic acid hydrazide 
• 617705-26-7 2-ethynyloxazole-4-carboxylic acid ethyl ester 
• 1107663-03-5 ethyl 2-iodo-1,3-oxazole-4-carboxylate 
• 78979-62-1 ethyl 2-(4-chlorophenyl)-1,3-oxazole-4-carboxylate 
• 886363-48-0 ethyl 2-(4-((tert-butoxycarbonyl)amino)phenyl)oxazole-4-carboxylate 
• 107367-69-1 C₁₄H₁₃NO₃ 
• 391248-23-0 ethyl 2-(4-bromphenyl)-1,3-oxazole-4-carboxylate 
• 885274-64-6 ethyl 2-(2-methoxyphenyl)oxazole-4-carboxylate 
• 1357944-10-5 ethyl 2-[4-(trifluoromethyl)phenyl]oxazole-4-carboxylate 

Relevant articles and documents

Rapid and convergent synthesis of a 2,4'-linked tri-oxazole in an approach to poly-oxazoles

A rapid and convergent synthesis of a 2,4'-linked tri-oxazole using a Negishi coupling is described.

Flow hydrodediazoniation of aromatic heterocycles

Continuous flow processing was applied for the rapid replacement of an aromatic amino group with a hydride. The approach was applied to a range of aromatic heterocycles, confirming the wide scope and substituent-tolerance of the processes. Flow equipment was utilized and the process optimised to overcome the problematically-unstable intermediates that have restricted yields in previous studies relying on batch procedures. Various common organic solvents were investigated as potential hydride sources. The approach has allowed key structures, such as amino-pyrazoles and aminopyridines, to be deaminated in good yield using a purely organic-soluble system.

Chemical Compounds

This invention relates to non-steroidal compounds that are modulators of androgen, glucocorticoid, mineralocorticoid, and progesterone receptors, and also to the methods for the making and use of such compounds.