39137-27-4Relevant academic research and scientific papers
Synthesis and anticonvulsant activity of new acylthiosemicarbazides and thiazolidines
Gursoy,Karali
, p. 857 - 866 (2007/10/03)
A number of 1-(3-phenyl-4(3H)-quinazolinone-2-ylmercaptoacetyl)-4-substituted thiosemicarbazide and 2-(3-phenyl-4(3H)-quinazolinone-2-ylmercaptoacetylhydrazono)-3-substit uted 4-thiazolidone derivatives were synthesized and evaluated for anticonvulsant ac
Influence of Substituents on the Synthesis of Thiazolidinones
Sabu, M.,Garnaik, B. K.,Behera, Rajani K.
, p. 779 - 781 (2007/10/02)
The influence of substituents (subunits) in the synthesis of thiazolidinones by the reaction of unsymmetrical thioureas with monochloroacetic acid in ethanol has been rationalised by the characterisation of the hydrolysis products of the resulting thiazolidinones.The formation of thiol from thiourea, which is the key intermediate in thiazolidinone synthesis, invariably involves the -NH- group adjacent to more electron withdrawing subunits.
