391594-68-6Relevant articles and documents
The first stereospecific synthesis of L-tetrahydrodipicolinic acid; A key intermediate of diaminopimelate metabolism
Caplan, Jennifer F.,Sutherland, Andrew,Vederas, John C.
, p. 2217 - 2220 (2007/10/03)
L-Tetrahydrodipicolinic acid 1, a key intermediate of diaminopimelate metabolism has been prepared in 6 steps and 23% overall yield from L-allylglycine 4. The key step during this synthesis involves a base mediated cyclisation of dimethyl (2RS,6S)-2-[N-(b