391645-97-9Relevant academic research and scientific papers
One-pot tandem synthesis of tetrasubstituted pyrazoles via 1,3-dipolar cycloaddition between aryl hydrazones and ethyl but-2-ynoate
Ningaiah, Srikantamurthy,Doddaramappa, Shridevi D.,Chandra,Madegowda, Mahendra,Keshavamurthy, Shubakara,Bhadraiah, Umesha K.
supporting information, p. 2222 - 2231 (2014/07/07)
1,3,4,5-Tetrasubstituted pyrazoles are rapidly and regioselectively synthesized in a one-pot, three-step sequence consisting of condensation, nitrilimine generation, and cycloaddition using mercuric acetate. Newly synthesized compounds were characterized by spectral studies. Regiochemistry of compounds 6a and 8a was determined as 1,4- and 1,5-regioisomers respectively by X-ray crystallography. Copyright
