391895-16-2Relevant academic research and scientific papers
Photomodulable phosphines incorporating diarylethene moieties
Bianchini, Giulio,Strukul, Giorgio,Wass, Duncan F.,Scarso, Alessandro
, p. 10795 - 10798 (2015)
Incorporation of the dithienylethene moiety as a substituent provides new 'switchable' phosphine ligands whose electronic properties are reversibly modulated by light. The presence of electron-withdrawing substituents in the photochromic unit increases th
Uni- and bi-directional light-induced switching of diarylethenes on gold nanoparticles
Kudernac, Tibor,Van Der Molen, Sense Jan,Van Wees, Bart J.,Feringa, Ben L.
, p. 3597 - 3599 (2006)
Photochromic studies of diarylethenes with their switching unit linked to the surface of gold nanoparticles via a conjugated aromatic spacer show linker-dependent switching behavior. The Royal Society of Chemistry 2006.
Acid-induced photochromic system switching of diarylethene derivatives between P- and T-types
Kobatake, Seiya,Terakawa, Yuko
, p. 1698 - 1700 (2007)
P-type photochromic diarylethenes having a diethylamino group can switch to T-type photochromic system by the addition of trifluoromethanesulfonic acid as external stimuli. The Royal Society of Chemistry.
Photoactivation of the cytotoxic properties of platinum(II) complexes through ligand photoswitching
Presa, Andreu,Vázquez, Guillem,Barrios, Leoní A.,Roubeau, Olivier,Korrodi-Gregório, Luís,Pérez-Tomás, Ricardo,Gamez, Patrick
, p. 4009 - 4022 (2018/04/10)
The development of photoactivatable metal complexes with potential anticancer properties is a topical area of current investigation. Photoactivated chemotherapy using coordination compounds is typically based on photochemical processes occurring at the metal center. In the present study, an innovative approach is applied that takes advantage of the remarkable photochemical properties of diarylethenes. Following a proof-of-concept study with two complexes, namely, C1 and C2, a series of additional platinum(II) complexes from dithienylcyclopentene-based ligands was designed and prepared. Like C1 and C2, these new coordination compounds exhibit two thermally stable, interconvertible photoisomers that display distinct properties. The photochemical behavior of ligands L3-L7 has been analyzed by 1H NMR and UV-vis spectroscopies. Subsequently, the corresponding platinum(II) complexes C3-C7 were synthesized and fully characterized, including by single-crystal X-ray diffraction for some of them. Next, the interaction of each photoisomer (i.e., containing the open or closed ligand) of the metal complexes with DNA was examined thoroughly using various techniques, revealing their distinct DNA-binding modes and affinities, as observed for the earlier compounds C1 and C2. The antiproliferative activity of the two forms of the complexes was then assessed with five cancer cell lines and compared with that of C1 and C2, which supported the use of such diarylethene-based systems for the generation of a new class of potential photochemotherapeutic metallodrugs.
Molecular switches get wired: Synthesis of diarylethenes containing one or two sulphurs
Kudernac,De Jong,Van Esch,Feringa,Dulic,Van Der Molen,Van Wees
, p. 205 - 210 (2007/10/03)
Two series of novel diarylethenes, the first containing one and the second two acetyl protected thiol groups, were synthesised in two and three steps from an easily available known intermediate. Newly synthesised compounds present ideal examples of model
Oxidative electrochemical switching in dithienylcyclopentenes, part 2: Effect of substitution and asymmetry on the efficiency and direction of molecular switching and redox stability
Browne, Wesley R.,De Jong, Jaap J. D.,Kudernac, Tibor,Walko, Martin,Lucas, Linda N.,Uchida, Kingo,Van Esch, Jan H.,Feringa, Ben L.
, p. 6430 - 6441 (2007/10/03)
The electrochemical and spectroelectrochemical properties of a series of C5-substituted dithienylhexahydro- and dithienylhexafluorocyclopentenes are reported. The effect of substitution at C5 of the thienyl moiety on the redox properties is quite dramatic
