39205-62-4

Basic information

• Product Name: 4-Choro-2(3H)-benzothiazolone
• Synonyms: 2-HYDROXY-4-CHLORO BENZOTHIOZOLE;4-CHLOROBENZOTHIAZOLONE;4-choro-2(3h)-benzothiazolone;4-chlorobenzothiazol-2(3H)-one;4-Chloro-2(3H)-benzothiazolone;2(3H)-Benzothiazolone,4-chloro-(9CI);4-CHARO-2(3H)BENZOTHIAZOLONE;Hydroxy chloro benzothiozole
• CAS NO: 39205-62-4
• Molecular Formula: C₇H₄ClNOS
• Molecular Weight: 185.63
• EINECS: 254-354-8
• Product Categories: BENZOTHIAZOLE;API intermediates
• Mol File: 39205-62-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 204-205°C
• Boiling Point: 394.2 °C at 760 mmHg
• Flash Point: 192.2 °C
• Appearance: /
• Density: 1.516 g/cm³
• Vapor Pressure: 8.85E-07mmHg at 25°C
• Refractive Index: 1.669
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 9.35±0.20(Predicted)
• CAS DataBase Reference: 4-Choro-2(3H)-benzothiazolone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Choro-2(3H)-benzothiazolone(39205-62-4)
• EPA Substance Registry System: 4-Choro-2(3H)-benzothiazolone(39205-62-4)

Safety Data

• Hazardous Substances Data: 39205-62-4(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C7H4ClNOS/c8-4-2-1-3-5-6(4)9-7(10)11-5/h1-3H,(H,9,10)

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Downstream Products

• 63755-05-5 4-chloro-N-methyl-2(3H)-benzothiazolone 

Relevant articles and documents

Self-assembly of a benzothiazolone conjugate into panchromatic fluorescent fibres and their application in cellular imaging

We report the synthesis and characterization of the structures formed by self-assembly of 4-chloro-2(3H)-benzothiazolone (CBT) into panchromatic fibres and their application in cellular imaging. The aggregation properties of the synthesized compound were studied extensively under different solvents and concentrations and their morphologies examined at a supramolecular level by various microscopic techniques such as atomic force microscopy (AFM), fluorescence microscopy, and optical microscopy. Interestingly, the self-assembled structures formed byCBTreveal panchromatic emission properties and show blue, green, and red fluorescence under different excitation wavelengths. The mechanism of structure formation of the self-assemblies was studied through different techniques such as concentration-dependent1H-NMR, ATR-FTIR, UV-visible spectroscopy, and fluorescence spectroscopy. Finally, the utility ofCBTfor cell imaging applications was demonstrated and it can be noted thatCBTwas efficiently taken up by mammalian cells and the cells revealed panchromatic emission in the blue, green, and red channels. The intensities of the fluorescence observed were blue > green > red and the dye interestingly does not exhibit any fluorescence quenching.

Analgesic and antipyretic pharmaceutical compositions containing a benzothiazol-2(3H)-one

Analgesic and antipyretic pharmaceutical dosage unit compositions containing as an active ingredient a compound of the formula STR1 wherein R5 is methyl or methoxy, and R4, R6 and R7 are hydrogen; or R6 is fluorine or chlorine, and R4, R5 and R7 are hydrogen; or R7 is chlorine, and R4, R5 and R6 are hydrogen; or R5 and R6 are methoxy, and R4 and R7 are hydrogen; or R4 is methyl or chlorine, and R5, R6 and R7 are hydrogen; and methods of using said compounds as analgesics and antipyretics.