39209-17-1

Upstream product

• 98-88-4 benzoyl chloride 
• 119-26-6 (2,4-dinitro-phenyl)-hydrazine 
• 93-97-0 benzoic acid anhydride 
• 584-48-5 2,4-dinitrobromobenzene 

Downstream Products

• 72619-63-7 3-(2,4-dinitro-phenyl)-2-ethoxy-5-phenyl-2,3-dihydro-[1,3,4]oxadiazole 
• 17359-83-0 N'-(2,4-dinitrophenyl)benzhydrazide 
• 63418-42-8 C₁₃H₈N₄O₅ 
• 17109-21-6 1-phenyl-propenone-((E)-2,4-dinitro-phenylhydrazone) 
• 20501-37-5 1-phenyl-propenone-((Z)-2,4-dinitro-phenylhydrazone) 
• 155951-44-3 N¹-(2,4-Dinitrophenyl)-N³-ethoxalyl-N²-benzamidrazone 
• 155951-47-6 ethyl 1-(2,4-dinitrophenyl)-3-phenyl-1,2,4-triazole-5-carboxylate 
• 155951-51-2 7-Amino-2-phenyl-5H-[1,2,4]triazolo[1,5-a]quinoxalin-4-one 
• 115591-33-8 C₁₃H₁₁N₅O₄ 

Relevant academic research and scientific papers

An approach to pyrazoline-fused chlorins by dipolar [3 + 2]-cycloaddition of iminonitriles to Meso-Tetrakis(pentafluorophenyl)porphyrin: Synthesis of new PDT photosensitizers

Meso-Tetrakis(pentafluorophenyl)porphyrin reacts at higher temperature with unstable iminonitriles (RC≡N+-N--Ar), affording pyrazoline-fused chlorins, according to dipolar [3 + 2]-cycloaddition pathway. The respective iminonitriles were in situ generated from the corresponding functionalized α-halogenohydrazine derivatives by 1,3-elimination of HX in the presence of base (NEt3, DABCO). This method allows synthesis of very attractive moieties which may be of potential use as sensitizers in photodynamic therapy (PDT).

Tricyclic heteroaromatic systems 1,2,4-triazolo[1,5-a]quinoxalines: Synthesis and benzodiazepine receptor activity

The synthesis, the benzodiazepine binding activity and the 'in vitro' biological effect of some 1,2,4-triazolo]1,5-a]quinoxalines, 3-aza-analogues of some previously reported pyrazolo[1,5-a]quinoxalines, are described. Molecular modelling is used to define the structural requirements of the benzodiazepine recognition site which influence the affinity and different efficacy of these rigid ligands.