3921-01-5Relevant articles and documents
Syntheses of various 5-(bromoaryl)-substituted uracils
Wellmar,Hornfeldt,Gronowitz
, p. 1159 - 1163 (1995)
The Suzuki Pd(0)-catalyzed coupling between arylboronic acids and aryl bromides or iodides in weakly alkaline medium, previously further developed by us, has been used for regioselective preparation of 5-(2'-bromo-5'-furyl)-, 5-(2'-bromo-4'-furyl)-, 5-(2'
Regio- and chemoselective multiple functionalization of pyrimidine derivatives by selective magnesiations using TMPMgCl·LiCl
Mosrin, Marc,Knochel, Paul
supporting information; experimental part, p. 2497 - 2500 (2009/05/30)
(Chemical Equation Presented) Successive regio- and chemoselective magnesiations of pyrimidines using TMPMgCl·LiCl furnish, after trapping with various electrophiles, highly functionalized derivatives in good to excellent yields. Applications to the synth
Arylation of halogenated pyrimidines via a suzuki coupling reaction
Schomaker,Delia
, p. 7125 - 7128 (2007/10/03)
The Suzuki coupling reaction has been used extensively for the synthesis of a wide variety of unsymmetrical biaryl compounds. We have extended this reaction to demonstrate the utility of preparing monophenyl-, diphenyl-, or triphenylpyrimidine depending on the reaction conditions. Further, it has been shown that chloropyrimidine substrates are preferable over iodo-, bromo-, or fluoropyrimidines.