392231-63-9Relevant articles and documents
Cyclic amine sulfonamides as linkers in the design and synthesis of novel human β3 adrenergic receptor agonists
Sum, Fuk-Wah,Wong, Victoria,Han, Stella,Largis, Elwood,Mulvey, Ruth,Tillett, Jeff
, p. 2191 - 2194 (2007/10/03)
Piperidine, pyrrolidine, and azetidine sulfonamides were examined as linkers in designing novel human β3 adrenergic receptor (β3-AR) agonists. The azetidine derivative 37, and piperidine derivatives 7, 8, and 13 were found to be potent β3-AR agonists and have good selectivity against β1- and β2-AR.