392250-83-8

Upstream product

• 392250-80-5 (R)-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-(4-methoxy-benzyloxy)-acetaldehyde 
• 392250-81-6 (S)-4-[(S)-1-(4-Methoxy-benzyloxy)-allyl]-2,2-dimethyl-[1,3]dioxolane 
• 142561-88-4 (S)-1-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)but-3-en-1-ol 
• 2746-25-0 p-Methoxybenzyl bromide 
• 93367-10-3 (2S,3S)-3,4-epoxy-1,2-di-O-isopropylidenebutane-1,2-diol 
• 1372785-52-8 (S)-4-((S)-1-(4-methoxybenzyloxy)but-3-enyl)-2,2-dimethyl-1,3-dioxolane 
• 392250-82-7 (S)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-3-(4-methoxybenzyloxy)-propan-1-ol 

Downstream Products

• 1372785-77-7 2-[(2S,3S,6R)-3-benzyloxy-6-((S)-6-hydroxyhept-1(Z)-enyl)tetrahydro-2H-pyran-2-yl]acetic acid 
• 1173181-30-0 2-[(2S,3S,6R)-3-benzyloxy-6-((S)-6-hydroxyhept-1(E)-enyl)tetrahydro-2H-pyran-2-yl]acetic acid 
• 1372785-48-2 (2S,11S,E)-dodec-6-ene-2,11-diol 
• 1211843-98-9 (1R,5S,11R,14S,9Z)-14-(benzyloxy)-5-methyl-4,15-dioxabicyclo[9.3.1]pentadec-9-en-3-one 
• 1372785-59-5 (6S,7S,E)-methyl 6-(benzyloxy)-9-(tert-butyldiphenylsilyloxy)-7-(4-methoxybenzyloxy)non-2-enoate 
• 1372785-60-8 (6S,7S,E)-6-(benzyloxy)-9-(tert-butyldiphenylsilyloxy)-7-(4-methoxybenzyloxy)non-2-en-1-ol 
• 1372785-51-7 (6S,7S,E)-6-(benzyloxy)-9-(tert-butyldiphenylsilyloxy)non-2-ene-1,7-diol 
• 1372785-50-6 (S)-1-((2R,5S,6S)-5-(benzyloxy)-6-(2-(tert-butyldiphenylsilyloxy)ethyl)-tetrahydro-2H-pyran-2-yl)ethane-1,2-diol 
• 1372785-63-1 (2-((2S,3S,6R)-3-(benzyloxy)-6-vinyl-tetrahydro-2H-pyran-2-yl)ethoxy)(tert-butyl)diphenylsilane 
• 1372785-64-2 2-((2S,3S,6R)-3-(benzyloxy)-6-vinyl-tetrahydro-2H-pyran-2-yl)ethanol 
• 1372785-49-3 2-((2S,3S,6R)-3-(benzyloxy)-6-vinyl-tetrahydro-2H-pyran-2-yl)acetic acid 
• 1372785-68-6 (3S,4S)-4-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)oct-7-en-3-ol 
• 1372785-69-7 (3R,4S)-4-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)oct-7-en-3-yl 4-nitrobenzoate 
• 1372785-70-0 (3R,4S)-4-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)oct-7-en-3-ol 

Relevant academic research and scientific papers

Formal total synthesis of aspergillides A and B

The formal total synthesis of the cytotoxic 14-membered macrolides, aspergillides A and B is described. A combination of a chiron approach and an asymmetric synthesis is adopted for the synthesis of the target macrolides. The required 2,6-syn and 2,6-anti

Synthetic studies on apoptolidin: Synthesis of the C1-C21 macrolide fragment

The stereoselective and convergent synthesis of the C1-C21 macrocyclic segment (2) of the apoptosis inducing macrolide antibiotic, apoptolidin (1), is described.