39236-04-9

Basic information

• Product Name: 1,3-Dithiane, 2-[4-(phenylmethoxy)phenyl]-
• CAS NO: 39236-04-9
• Molecular Formula: C17H18OS2
• Molecular Weight: 302.461
• Mol File: 39236-04-9.mol

Chemical Properties

• CAS DataBase Reference: 1,3-Dithiane, 2-[4-(phenylmethoxy)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dithiane, 2-[4-(phenylmethoxy)phenyl]-(39236-04-9)
• EPA Substance Registry System: 1,3-Dithiane, 2-[4-(phenylmethoxy)phenyl]-(39236-04-9)

Safety Data

• Hazardous Substances Data: 39236-04-9(Hazardous Substances Data)

Upstream product

• 109-80-8 1.3-propanedithiol 
• 4397-53-9 p-benzyloxybenzaldehyde 

Downstream Products

• 4397-53-9 p-benzyloxybenzaldehyde 

Relevant articles and documents

Solid-supported odorless reagents for the dithioacetalization of aldehydes and ketones

A solid supported, odorless reagent for the dithioacetalization of aldehydes and ketones has been developed. The new reagent provides the dimercaptoalkane equivalent in combination with stoichiometric amounts of immobilized acid and enables the formation of dithianes and dithiolanes from aldehydes without any additives in good to very good yields with high purities. The reaction is chemoselective for aldehydes, but ketones can be reacted to the corresponding dithioketals if an additional Lewis acid such as BF3is added.

C-ARYL GLYCOSIDE COMPOUNDS FOR THE TREATMENT OF DIABETES AND OBESITY

This invention relates to a compound of generic formula (I): (I) as well as a pharmaceutically acceptable salt thereof, a tautomer, optical isomer or a mixture of optical isomers in any proportion, in particular a mixture of enantiomers, and particularly a racemate mixture, in particular for use thereof as a drug, notably in the treatment of diabetes.

An efficient, continuous flow technique for the chemoselective synthesis of thioacetals

By optimizing a reagent's residence time within a packed-bed reactor, it is possible to overcome selectivity issues frequently encountered in stirred reaction vessels. This important feature is demonstrated for the chemoselective protection of 4-acetylben

Silica-supported perchloric acid (HClO4-SiO2): A versatile catalyst for tetrahydropyranylation, oxathioacetalization and thioacetalization

A simple and convenient synthetic protocol for the protection of hydroxyl group as tetrahydropyranyl ether as well as carbonyl functionality as oxathioacetal and thioacetal has been achieved using a catalytic amount of silica-supported perchloric acid und

A simple and practical synthetic protocol for thioacetalization of carbonyl compounds

Various aldehydes and ketones are smoothly converted to the corresponding acyclic and cyclic dithioacetals in very good yields by employing catalytic amount of acetyl chloride at room temperature under solvent-free conditions. Some of the major advantages of this procedure are its mild reaction conditions, highly efficient and selective, good yields, economically cheaper and compatible in the presence of a wide variety of other protecting groups.

Selective thioacetalization of aldehydes catalyzed by aqueous zinc tetrafluoroborate

A wide range of cyclic dithioacetals are prepared from the corresponding aldehydes in the presence of aqueous solution of zinc tetrafluoroborate.

Cobalt(II)chloride catalyzed chemoselective thioacetalization of aldehydes

A mild and chemoselective dithioacetalization procedure for the protection of various aldehydes in the presence of catalytic amount of cobalt(II)chloride is described.

Chemoselective thioacetalisation and transthioacetalisation of carbonyl compounds catalysed by tetrabutylammonium tribromide (TBATB)

Thioacetals and thioketals of various aldehydes and ketones were obtained directly from carbonyl compounds or by a transthioacetalisation process from cyclic O,O-acetals in the presence of dithiols and a catalytic amount of tetrabutylammonium tribromide (TBATB). Chemoselective thioacetalisation of aromatic aldehydes containing an electron-donating group in the presence of an aldehyde containing an electron-withdrawing group, aldehydes in the presence of ketones, aliphatic cyclic ketones in the presence of aromatic ketones and less hindered ketones in the presence of more hindered ketones have been achieved. A cyclic acetal containing an electron-donating group has been chemoselectively transthioacetalised in the presence of an acetal having an electron-withdrawing substituent. These selectivities are due to the intrinsic reactivity of the substrate themselves and are independent of the catalyst and reaction conditions, Shorter reaction times, mild reaction conditions, stability of acid sensitive protecting groups, high efficiencies, facile isolation of the desired products and the catalytic nature of the reagent are the attractive features of the present method.

Nickel(II) chloride as an efficient and useful catalyst for chemoselective thioacetalization of aldehydes

A wide variety of acyclic and cyclic dithioacetals can be prepared chemoselectively from the corresponding aldehydes by employing a catalytic amount of nickel(II) chloride in dry CH2Cl2-MeOH (5:1) at room temperature in good yields.