3924-22-9

Basic information

• Product Name: 11-BETA-HYDROXYANDROSTENEDIOL
• Synonyms: 11-BETA-HYDROXYANDROSTENEDIOL;5-ANDROSTEN-3-BETA, 11-BETA, 17-BETA-TRIOL;5-Androstene-3B,11B,17B-triol;Androst-5-ene-3β,11β,17β-triol
• CAS NO: 3924-22-9
• Molecular Formula: C19H30O3
• Molecular Weight: 306.44
• Mol File: 3924-22-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 11-BETA-HYDROXYANDROSTENEDIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 11-BETA-HYDROXYANDROSTENEDIOL(3924-22-9)
• EPA Substance Registry System: 11-BETA-HYDROXYANDROSTENEDIOL(3924-22-9)

Safety Data

• Hazardous Substances Data: 3924-22-9(Hazardous Substances Data)

Usage

General Description

11-BETA-HYDROXYANDROSTENEDIOL, also known as 11β-Hydroxyandrostenedione, is a steroid hormone with a hydroxyl group at the 11th position. It is an intermediate in the biosynthesis of steroid hormones, particularly estrogen and androgen. This chemical has been studied for its potential role in hormone-related conditions and diseases, including breast cancer and polycystic ovary syndrome. Research suggests that 11-BETA-HYDROXYANDROSTENEDIOL may have implications in the regulation of hormonal balance and may serve as a biomarker for certain hormone-related disorders. Overall, this chemical plays a crucial role in the endocrine system and has the potential for further exploration in the field of hormone regulation and related disorders.

Upstream product

• 1816-85-9 11β-hydroxytestosterone 
• 17520-04-6 3-acetoxyandrosta-3,5-diene-11,17-dione 
• 382-45-6 adrenosterone 

Downstream Products

• 17520-02-4 3β-Hydroxy-androsten-(5)-dion-(11,17) 
• 82251-59-0 dehydro-oogoniol 
• 82251-59-0 dehydro-oogoniol 

Relevant articles and documents

Raw synthesis and mitochondrial function postischemic mitochondria diseases related to the lack or for use in new compd. 11β-hydroxysteroid

The present invention provides novel compounds of 112-hydroxy steroids and compositions and their application as pharmaceuticals for preventing or reversing injury to mitochondria, for treating or preventing diseases relating to mitochondrial dysfunction or depletion, and for inducing regeneration or restructuring of mitochondria as a means of treating diseases relating to abnormalities in mitochondrial structure and function in a human or animal subject. Also disclosed herein are methods for diagnosing injury to mitochondria and for diagnosing the success or failure of therapeutics designed to treat, prevent, or reverse injury to or depletion of mitochondria.

Synthesis of Oogoniol

Oogoniol , a female-activating hormone of Achlya, has been synthesized from 4-androstene-3,11,17-trione.A novel step involved 1,4-addition of the magnesium cyanocuprate derivative of (S)-3-(1-methylethyl)-5-pentyl bromide to 3β-hydroxy-15β,16β-epoxy-11-oxo-(17(20)E)-pregna-5,17(20)-diene 3-tert-butyldimethylsilyl ether.Selective hydrogenation of the resulting Δ16 double bond gave only the stigmastene product with the correct stereochemistry at C15, C17, and C20.