39243-88-4 Usage
Uses
Used in Pharmaceutical Development:
2-(1-Pyrrolyl)benzylamine is used as a key intermediate in the synthesis of pharmaceutical drugs for its potential as a serotonin receptor agonist. This application is crucial for the development of medications targeting various neurological and psychiatric disorders where modulation of serotonin levels is beneficial.
Used in Organic Synthesis:
In the field of organic synthesis, 2-(1-Pyrrolyl)benzylamine serves as a versatile building block for creating novel chemical compounds with diverse biological activities. Its unique structure allows for the formation of a wide array of derivatives, expanding the scope of chemical research and innovation.
Used in Medicinal Chemistry Research:
2-(1-Pyrrolyl)benzylamine is utilized in medicinal chemistry research as a compound with potential biological activities. Its exploration contributes to the understanding of structure-activity relationships and aids in the design of more effective and targeted therapeutic agents.
Used in Chemical Compound Design:
In the design of chemical compounds, 2-(1-Pyrrolyl)benzylamine is used as a structural element to introduce specific properties or reactivity. Its incorporation can lead to the development of new materials with unique characteristics, applicable in various industries such as pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 39243-88-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,2,4 and 3 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 39243-88:
(7*3)+(6*9)+(5*2)+(4*4)+(3*3)+(2*8)+(1*8)=134
134 % 10 = 4
So 39243-88-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H12N2/c12-9-10-5-1-2-6-11(10)13-7-3-4-8-13/h1-8H,9,12H2
39243-88-4Relevant academic research and scientific papers
Bronsted Acid Catalyzed Cyclization of Inert N-Substituted Pyrroles to Benzo[ f ]pyrrolo[1,2- a ][1,4]diazepines
Gao, Zeng,Qian, Jinlong,Yang, Huameng,Zhang, Jinlong,Jiang, Gaoxi
, p. 930 - 934 (2021/04/27)
Two approaches involving intramolecular and intermolecular cyclization, respectively, have been developed for the direct and practical construction of a series of important benzo[ f ]pyrrolo[1,2- a ][1,4]azepines by using Bronsted acid catalysts. Upon catalysis by TsOH, the intramolecular dehydroxylation/ring closure of 3-hydroxy-2-[2-(1 H -pyrrol-1-yl)benzyl]isoindolin-1-ones provided various racemic benzo[ f ]pyrrolo[1,2- a ][1,4]azepines in high yields. Furthermore, enantioenriched benzo[ f ]pyrrolo[1,2- a ][1,4]azepines were also obtained by chiral phosphoric acid catalyzed intermolecular addition of [2-(1 H -pyrrol-1-yl)phenyl]methanamines to 2-formylbenzoates under mild conditions.
Pyrrolo[1,2-a][1,4]benzodiazepine: A novel class of non-azole anti-dermatophyte anti-fungal agents
Meerpoel, Lieven,Van Gestel, Jef,Van Gerven, Frans,Woestenborghs, Filip,Marichal, Patrick,Sipido, Vic,Terence, Gilkerson,Nash, Roger,Corens, David,Richards, Ray D.
, p. 3453 - 3458 (2007/10/03)
Broad screening revealed compound 1a to be a novel anti-fungal agent with high specificity towards dermatophytes. The anti-fungal structure-activity relationship of this novel class of 5,6-dihydro-4H-pyrrolo[1,2-a][1,4] benzodiazepines is described togeth
