39254-87-0

Basic information

• Product Name: Methanone, (2-aminophenyl)-2-thiazolyl-
• CAS NO: 39254-87-0
• Molecular Formula: C10H8N2OS
• Molecular Weight: 204.252
• Mol File: 39254-87-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Methanone, (2-aminophenyl)-2-thiazolyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (2-aminophenyl)-2-thiazolyl-(39254-87-0)
• EPA Substance Registry System: Methanone, (2-aminophenyl)-2-thiazolyl-(39254-87-0)

Safety Data

• Hazardous Substances Data: 39254-87-0(Hazardous Substances Data)

Upstream product

• 161988-57-4 2-formamidophenyl-2'-thiazolylketone 
• 552-89-6 2-nitro-benzaldehyde 
• 610-14-0 2-nitrobenzyl chloride 
• 39264-15-8 (2-nitrophenyl)-(2-thiazolyl)methanol 
• 135531-86-1 camalexin 
• 39264-16-9 2-nitrophenyl-2'-thiazolylketone 

Downstream Products

• 135531-86-1 camalexin 
• 39481-64-6 [2-(2-bromo-acetylamino)-5-iodo-phenyl]-thiazol-2-yl-methanone 
• 168161-79-3 [1-(3,3-Dimethyl-2-oxo-butyl)-2-oxo-5-thiazol-2-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-carbamic acid benzyl ester 
• 168161-78-2 (2-Oxo-5-thiazol-2-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-carbamic acid benzyl ester 
• 161988-57-4 2-formamidophenyl-2'-thiazolylketone 
• 39254-78-9 (2-amino-5-iodo-phenyl)-thiazol-2-yl-methanone 
• 39264-18-1 [2-(2-bromo-acetylamino)-phenyl]-thiazol-2-yl-methanone 

Relevant articles and documents

AMIDE DERIVATIVES AS SIRTUIN MODULATORS

Provided herein are novel sirtuin-modulating compounds represented by Structural Formula (I) and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benfit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin- modulating compound in combination with another therapeutic agent.

Syntheses of Camalexin, Indolopyridocoline and Flavopereirine

A short synthetic route to the phytoalexin camalexin 7 and a convergent approach to the alkaloids indolopyridocoline 8, 6,7-dihydroflavopereirine 15 and flavopereirine 9 are presented.Starting from well accessible precursors, these total syntheses highlight the preparative potential of a new method for indole synthesis based on the formation of the C2-C3 bond by low-valent titanium induced reductive coupling of oxo-amides.