39265-57-1

Basic information

• Product Name: (+)-COREY LACTONE, 4-PHENYLBENZOATE ALCOHOL
• Synonyms: (3aR,4S,5R,6aS)-(-)-Hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl 1,1'-biphenyl-4-carboxylate;(+)-COREY LACTONE, 4-PHENYLBENZOATE ALCOHOL;(3aS,4R,5S,6aR)-(+)-Hexahydro-4-(hydroxymethyl)-5-(4-phenylbenzoyloxy)cyclopenta[b]-furan-2-one;(3aS,4R,5S,6aR)-Hexahydro-4-hydroxymethyl-5-(4-phenylbenzyloxy)cyclopenta[b]furan-2-one;(3aS,4R,5S,6aR)-Hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl Ester [1,1'-Biphenyl]-4-carboxylic Acid
• CAS NO: 39265-57-1
• Molecular Formula: C₂₁H₂₀O₅
• Molecular Weight: 352.38
• Product Categories: Chiral Building Blocks;Lactones;Organic Building Blocks
• Mol File: 39265-57-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 134-136 °C(lit.)
• Boiling Point: 584.8°C at 760 mmHg
• Flash Point: 210.6°C
• Appearance: /
• Density: 1.32
• Vapor Pressure: 1.61E-14mmHg at 25°C
• Refractive Index: 1.628
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: (+)-COREY LACTONE, 4-PHENYLBENZOATE ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-COREY LACTONE, 4-PHENYLBENZOATE ALCOHOL(39265-57-1)
• EPA Substance Registry System: (+)-COREY LACTONE, 4-PHENYLBENZOATE ALCOHOL(39265-57-1)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 39265-57-1(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 39265-57-1 differently. You can refer to the following data:
1. (3aS,4R,5S,6aR)-Hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl Ester [1,1'-Biphenyl]-4-carboxylic Acid is a corey lactone derivative and a key intermediate in the synthesis of prostaglan dins.
2. (3aS,4R,5S,6aR)-Hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl Ester [1,1''-Biphenyl]-4-carboxylic Acid is a corey lactone derivative and a key intermediate in the synthesis of prostaglandins.

InChI:InChI=1/C21H20O5/c22-12-17-16-10-20(23)25-18(16)11-19(17)26-21(24)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-9,16-19,22H,10-12H2/t16-,17-,18+,19-/m1/s1

Upstream product

• 136982-10-0 <3aS(3aα,4α,5β,6aα)>-(+)-<5-(1,1'-biphenyl-4-carbonyloxy)hexahydro-2H-cyclopentafuran-2-on-4-yl>methyl hydrogen butanedioate 
• 136982-11-1 <3aS(3aα,4α,5β,6aα)>-(+)-<5-(1,1'-biphenyl-4-carbonyloxy)hexahydro-2H-cyclopentafuran-2-on-4-yl>methyl hydrogen pentanedioate 
• 127783-76-0 <3aS(2aα,4α,5β,6aα)>-(+)-5-(1,1'-biphenyl-4-carbonyloxy)-4-(butyryloxymethyl)hexahydro-2H-cyclopentafuran-2-one 
• 76704-05-7 <3aS(3aα,4α,5β,6aα)>-(+)-5-hydroxy-4-hydroxymethyl-hexahydro-2H-cyclopentafuran-2-one 
• 14002-51-8 4-biphenyl-carboxylic acid chloride 
• 54382-73-9 <3aR(3aα,4α,5β,6aα)>-(-)-5-(1,1'-biphenyl-4-carbonyloxy)hexahydro-4-hydroxymethyl-2H-cyclopentafuran-2-one 

Downstream Products

• 76704-05-7 <3aS(3aα,4α,5β,6aα)>-(+)-5-hydroxy-4-hydroxymethyl-hexahydro-2H-cyclopentafuran-2-one 
• 197523-93-6 (Z)-7-[(1S,2R,3S,5R)-5-Acetoxy-2-hydroxymethyl-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-hept-5-enoic acid methyl ester 
• 64982-35-0 (3aS,4R,5S,6aR)-hexahydro-5-(biphenyl-4-formyloxy)-4-(tert-butyldimethylsilyloxy methyl)-2H-cyclopenta[b]furan-2-one 

Relevant articles and documents

RESOLUTION OF A RACEMIC COREY LACTONE via ENANTIOSELECTIVE ESTERIFICATION

The (-)-enantiomer of Corey lactone Ia has been separated from its (+)-enantiomer Ib via enantioselective esterification of the latter using glycerol tributyrate and a catalytic amount of lipase from Candida cylindracea (EC 3.1.1.3) in an aprotic solvent

11,15-Epiprostaglandin E 2 and its enantiomer. Biological activity and synthesis.

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