392663-65-9

Upstream product

• 157240-43-2 (4R)-4,5-isopropylidenedioxy-1-(dimethoxyphosphoryl)-2-pentanone 
• 392663-28-4 (S)-4-(2-[1,3]Dithian-2-yl-ethyl)-2,2-dimethyl-[1,3]dioxolane 
• 392663-03-5 (E)-(2R,4S,7S)-8-Benzyloxy-7-methyl-oct-5-ene-1,2,4-triol 
• 392663-00-2 (E)-(S)-6-Benzyloxy-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-5-methyl-hex-3-en-2-one 
• 392663-01-3 (E)-(2S,5S)-6-Benzyloxy-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-5-methyl-hex-3-en-2-ol 
• 392663-05-7 (2R,3S,5R)-2-((1S,2R)-3-Benzyloxy-1-iodo-2-methyl-propyl)-5-hydroxymethyl-tetrahydro-furan-3-ol 
• 392663-09-1 (S)-3-[(2S,3S,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-2-methyl-propionaldehyde 
• 392663-30-8 3-(2-{(S)-2-[(2S,3S,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-1-methyl-ethyl}-[1,3]dioxolan-2-yl)-1-{2-[2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-[1,3]dithian-2-yl}-propan-1-ol 
• 392663-32-0 3-(2-{(S)-2-[(2S,3S,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-1-methyl-ethyl}-[1,3]dioxolan-2-yl)-1-{2-[2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-[1,3]dithian-2-yl}-propan-1-one 
• 392663-36-4 C₄₃H₅₄O₇S₂Si 
• 392663-38-6 C₄₀H₄₈O₈Si 
• 392663-46-6 C₄₀H₅₀O₈Si 
• 392663-48-8 C₄₀H₅₀O₈Si 
• 392663-34-2 C₃₆H₅₀O₆S₂Si 

Relevant academic research and scientific papers

Synthesis of the ABCD ring system of azaspiracid

Previously attempted spirocyclizations to form the ABCD ring system of azapiracid (1) have proven unsuccessful owing to the anomeric effects that favor the formation of the undesired 13S diastereomer. By the use of a hydrogen bond donor as an auxiliary gr