392674-84-9

Upstream product

• 392674-91-8 C₁₀H₁₇NO₂ 
• 701-99-5 Phenoxyacetyl chloride 

Downstream Products

• 392675-05-7 (3R,4S)-4-((S)-1,2-Dihydroxy-ethyl)-1-(2-methyl-allyl)-3-phenoxy-azetidin-2-one 
• 392675-17-1 (+)-(3R,4R)-4-formyl-3-phenoxy-1-(2-methyl-2-propenyl)-2-azetidinone 

Relevant academic research and scientific papers

Rapid entry to enantiopure carbacepham derivatives via Lewis acid promoted carbonyl-ene cyclization of 2-azetidinone-tethered alkenylaldehydes

(Matrix Presented) Lewis acid promoted types I and II carbonyl-ene cyclizations of 2-azetidinone-tethered alkenylaldehydes are used for the rapid, highly diastereoselective synthesis of polyfunctionalized, enantiomerically pure carbacepham derivatives.

Lewis acid-assisted ene cyclization of 2-azetidinone-tethered enals: Synthesis of enantiopure carbacepham derivatives

Diastereocontrolled Lewis acid-catalyzed preparation of enantiopure carbacepham derivatives have been developed starting from 2-azetidinone-tethered enals. The BF3.Et2O-promoted reaction of alkenylaldehydes 1 and 16 is effective as c