39269-74-4

Usage

Chemical structure

1-benzyl-2-methyl-1H-imidazole-5-carbaldehyde is a derivative of imidazole with a benzyl group attached to the nitrogen atom and an aldehyde functional group.

Applications

It is commonly used in organic synthesis and medicinal chemistry.

Building block

The presence of the aldehyde functional group makes it a versatile building block for the synthesis of various pharmaceuticals and biologically active compounds.

Antibacterial and antifungal properties

It is known for its potential antibacterial and antifungal properties.

Drug development

It has been studied for its potential use in the development of new drugs.

Reagent

It has shown potential as a reagent for the synthesis of heterocyclic compounds.

Intermediate

It is a valuable intermediate in the production of various pharmaceuticals and agrochemicals.

Upstream product

• 100-39-0 benzyl bromide 
• 35034-22-1 2-methyl-1H-imidazole-4-carboxaldehyde 
• 19673-09-7 N-benzylacetimidamide hydrochloride 
• 100-46-9 benzylamine 
• 35034-22-1 2-methylimidazole-4⁽⁵⁾-carbaldehyde 

Downstream Products

• 41030-20-0 3-(3-benzyl-2-methyl-3H-imidazol-4-yl)-1-[1,3]dioxolan-2-yl-4-methyl-pentan-3-ol 
• 41030-19-7 2-(3-benzyl-2-methyl-3H-imidazol-4-yl)-4-[1,3]dioxolan-2-yl-butan-2-ol 
• 41030-16-4 1-(3-benzyl-2-methyl-3H-imidazol-4-yl)-3-[1,3]dioxolan-2-yl-propan-1-one 
• 41030-24-4 1-benzyl-5-(3-[1,3]dioxolan-2-yl-propyl)-2-methyl-1H-imidazole 
• 41030-01-7 1-(3-benzyl-2-methyl-3H-imidazol-4-yl)-3-[1,3]dioxolan-2-yl-propan-1-ol 

Relevant academic research and scientific papers

METHOD FOR PREPARATION OF BENZIMIDAZOLE DERIVATIVES

The present invention provides a method for preparing a compound with a benzimidazole structure with an excellent yield using a low-cost starting material, not requiring an additional separation process, or not using a dangerous reagent during the manufacturing process. Furthermore, the present invention also provides an intermediate and a final product produced by the preparing method.

Imidazoles: SAR and development of a potent class of cyclin-dependent kinase inhibitors

An imidazole series of cyclin-dependent kinase (CDK) inhibitors has been developed. Protein inhibitor structure determination has provided an understanding of the emerging structure activity trends for the imidazole series. The introduction of a methyl sulfone at the aniline terminus led to a more orally bioavailable CDK inhibitor that was progressed into clinical development.

Imidazolo-5-YL-2anilino-pyrimidines as agents for the inhibition of the cell proliffration

Compounds of the formula (I): wherein R1, R2, R3, R4, R5, R6, p, q, and n are as defined within and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell cycle inhibitory (anti-cell-proliferation) effect in a warm-blooded animal, such as man.