392691-68-8

Basic information

• Product Name: 1-(2,5-difluoro-benzyl)-3-[4-(4-formyl-piperidine-1-sulfonyl)-phenyl]-1-isopropyl-urea
• Synonyms: 1-(2,5-difluoro-benzyl)-3-[4-(4-formyl-piperidine-1-sulfonyl)-phenyl]-1-isopropyl-urea
• CAS NO: 392691-68-8
• Molecular Weight: 479.548
• Mol File: 392691-68-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(2,5-difluoro-benzyl)-3-[4-(4-formyl-piperidine-1-sulfonyl)-phenyl]-1-isopropyl-urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,5-difluoro-benzyl)-3-[4-(4-formyl-piperidine-1-sulfonyl)-phenyl]-1-isopropyl-urea(392691-68-8)
• EPA Substance Registry System: 1-(2,5-difluoro-benzyl)-3-[4-(4-formyl-piperidine-1-sulfonyl)-phenyl]-1-isopropyl-urea(392691-68-8)

Safety Data

• Hazardous Substances Data: 392691-68-8(Hazardous Substances Data)

Upstream product

• 120434-27-7 trichloromethyl silane 
• 392691-67-7 1-(2,5-difluoro-benzyl)-3-[4-(4-dimethoxymethyl-piperidine-1-sulfonyl)-phenyl]-1-isopropyl-urea 
• 2991-28-8 2,5-difluorobenzoic acid 
• 392690-89-0 4-(4-dimethoxymethyl-piperidine-1-sulfonyl)-phenylamine 
• 392691-66-6 2,5-Difluoro-N-isopropyl-benzylamine 

Relevant articles and documents

Substituted 2- (S) -hydroxy-3- (piperidin-4-yl-methylamino) -propyl ethers and substituted 2-aryl-2- (R) - hydroxy-1- (piperidin-4-yl-methyl) -ethylamine beta-3 adrenergic receptor agonists

This invention provides compounds of Formula I having the structure wherein A, B, Z, R and R1 are as defined hereinbefore, or a pharmaceutically acceptable salt thereof, which are useful in treating or inhibiting metabolic disorders related to insulin resistance or hyperglycemia (typically associated with obesity or glucose intolerance), atherosclerosis, gastrointestinal disorders, neurogenetic inflammation, glaucoma, ocular hypertension and frequent urination; and are particularly useful in the treatment or inhibition of type II diabetes.