39271-12-0Relevant academic research and scientific papers
1-Hydroxy-1-[(4'-hydroxy-3'aminosulfonamido)-phenyl]-2-amino-ethanes and salts
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, (2008/06/13)
Compounds of the formula STR1 wherein R1 is hydrogen or methyl, and R2 is phenoxy-(alkyl of 2 to 3 carbon atoms), phenyl-(alkyl of 4 to 5 carbon atoms), hydroxyphenyl-(alkyl of 3 to 5 carbon atoms), or naphthyl-(alkyl of 4 to 5 carbo
N,N'-BIS[2-3-SUBSTITUTED-4-HYDROXYPHENYL)-2-HYDROXYETHYL)]-POLYMETHYLENEDIAMINES
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, (2008/06/13)
N,N'-Bis 2-(3-substituted-4-hydroxyphenyl)-ethyl or-2-hydroxyethyl!-polymethylenediamines having β-adrenergic stimulant activity particularly as selective bronchodilators, are prepared generally by condensation of an N-benzylphenethylamine with a polymethylene dihalide or by reaction of an α-bromoacetophenone with an N,N'-dibenzyl-polymethylenediamine, with further operations depending on the nature of the 3-substituent, and subsequently hydrogenating catalytically with for example palladium-on-carbon. The key intermediates are also part of the invention.
