393-38-4 Usage
Uses
Used in Chemical Research:
2,5-difluorobenzotrifluoride is used as a chemical intermediate for the synthesis of various organic compounds. Its unique structure and reactivity make it a valuable starting material for the development of new molecules with specific properties.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,5-difluorobenzotrifluoride is used as a building block for the development of new drugs. Its fluorinated nature can potentially enhance the pharmacokinetic and pharmacodynamic properties of the resulting drug molecules, leading to improved efficacy and safety profiles.
Used in Material Science:
2,5-difluorobenzotrifluoride can be utilized in the development of advanced materials, such as polymers and coatings, due to its unique chemical and physical properties. The incorporation of fluorine atoms can impart specific characteristics, such as increased stability, resistance to environmental factors, and improved performance under various conditions.
Used in the Studies of Rhodium NHC Catalyzed Hydrodefluorination of Polyfluorotoluenes:
2,5-difluorobenzotrifluoride is used as a substrate in the studies of the rhodium NHC (N-heterocyclic carbene) catalyzed hydrodefluorination of polyfluorotoluenes. This research area is important for understanding the reactivity and selectivity of fluorinated aromatic compounds, which can lead to the development of new catalytic systems and synthetic methods for the preparation of valuable chemicals and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 393-38-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,9 and 3 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 393-38:
(5*3)+(4*9)+(3*3)+(2*3)+(1*8)=74
74 % 10 = 4
So 393-38-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H3F5/c8-4-1-2-6(9)5(3-4)7(10,11)12/h1-3H
393-38-4Relevant academic research and scientific papers
Reactions of aromatic compounds with xenon difluoride
Bardin,Adonin, N. Yu.
, p. 1400 - 1407 (2016/11/29)
Reactions of substituted benzenes C6H5R (R = Me, F, Cl, Br, CF3, NO2) with xenon difluoride in the presence of boron trifluoride–diethyl ether complex in weakly acidic (1,1,1,3,3-pentafluorobutane) and weakly basic media (acetonitrile) have been studied. These reactions lead to the formation of fluorobenzene derivatives FC6H4R (isomer mixture) together with isomeric difluorobenzenes and fluorinated and non-fluorinated biphenyls. The results have been compared with previously reported data obtained in other solvents using other catalysts.
Mechanistic studies of the rhodium NHC catalyzed hydrodefluorination of polyfluorotoluenes
Schwartsburd, Leonid,Mahon, Mary F.,Poulten, Rebecca C.,Warren, Mark R.,Whittlesey, Michael K.
, p. 6165 - 6170 (2015/02/19)
The six-membered-ring NHC complexes Rh(6-NHC)(PPh3)2H (6-NHC = 6-iPr (1), 6-Et (2), 6-Me (3)) have been employed in the catalytic hydrodefluorination (HDF) of C6F5CF3 and 2-C6Fs
