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(R)-2-(4-bromophenyl)-2-hydroxyacetamide is a chemical compound with the molecular formula C8H9BrNO2. It is an amide derivative of 4-bromophenylacetic acid, characterized by a hydroxy group and an amide functional group attached to a 4-bromophenyl ring. (R)-2-(4-bromophenyl)-2-hydroxyacetamide is known for its versatile properties, making it a valuable building block in the synthesis of various pharmaceuticals. Additionally, it serves as a chiral auxiliary in asymmetric synthesis, which is crucial for the development of enantioselective strategies in organic chemistry.

393531-26-5

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393531-26-5 Usage

Uses

Used in Pharmaceutical Synthesis:
(R)-2-(4-bromophenyl)-2-hydroxyacetamide is used as a building block for the synthesis of various pharmaceuticals due to its unique structure and functional groups. Its presence in the molecular framework can contribute to the desired biological activity of the final drug product.
Used as a Chiral Auxiliary in Asymmetric Synthesis:
In the field of organic synthesis, (R)-2-(4-bromophenyl)-2-hydroxyacetamide is utilized as a chiral auxiliary. This application is significant for the development of enantioselective strategies, which are essential for creating compounds with specific stereochemistry, often crucial for the compound's biological activity and safety.
Used in Medicinal Chemistry and Drug Discovery:
The chiral nature and functional groups of (R)-2-(4-bromophenyl)-2-hydroxyacetamide make it an important compound in medicinal chemistry and drug discovery. It can be employed to design and develop new drugs with improved efficacy and selectivity, contributing to the advancement of therapeutic treatments for various diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 393531-26-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,3,5,3 and 1 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 393531-26:
(8*3)+(7*9)+(6*3)+(5*5)+(4*3)+(3*1)+(2*2)+(1*6)=155
155 % 10 = 5
So 393531-26-5 is a valid CAS Registry Number.

393531-26-5Downstream Products

393531-26-5Relevant academic research and scientific papers

Biocatalytic reduction of α-keto amides to (R)-α-hydroxy amides using Candida parapsilosis ATCC 7330

Stella, Selvaraj,Chadha, Anju

, p. 345 - 352 (2013/01/15)

Biocatalytic reduction of primary and secondary α-keto amides was accomplished using whole cells of Candida parapsilosis ATCC 7330. The primary (R)-α-hydroxy amides were obtained in good enantiomeric excess (up to 94%) and conversion (88-99%) as compared to the secondary (R)-α-hydroxy amides.

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