393590-66-4Relevant academic research and scientific papers
A novel approach for the development of selective Cdk4 inhibitors: Library design based on locations of Cdk4 specific amino acid residues
Honma,Yoshizumi,Hashimoto,Hayashi,Kawanishi,Fukasawa,Takaki,Ikeura,Ikuta,Suzuki-Takahashi,Hayama,Nishimura,Morishima
, p. 4628 - 4640 (2001)
Identification of a selective inhibitor for a particular protein kinase without inhibition of other kinases is critical for use as a biological tool or drug. However, this is very difficult because there are hundreds of homologous kinases and their kinase
