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Carbamic acid, dimethyl-, 4-methyl-2-oxo-3-(phenylmethyl)-2H-1-benzopyran-7-yl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

393810-34-9

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393810-34-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 393810-34-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,3,8,1 and 0 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 393810-34:
(8*3)+(7*9)+(6*3)+(5*8)+(4*1)+(3*0)+(2*3)+(1*4)=159
159 % 10 = 9
So 393810-34-9 is a valid CAS Registry Number.

393810-34-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-benzyl-4-methyl-2-oxo-2H-chromen-7-yl dimethylcarbamate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:393810-34-9 SDS

393810-34-9Downstream Products

393810-34-9Relevant academic research and scientific papers

Substituted 3-benzylcoumarins as allosteric MEK1 inhibitors: Design, synthesis and biological evaluation as antiviral agents

Wang, Chao,Zhang, Hao,Xu, Fengrong,Niu, Yan,Wu, Yun,Wang, Xin,Peng, Yihong,Sun, Jing,Liang, Lei,Xu, Ping

, p. 6057 - 6091 (2013/06/27)

In order to find novel antiviral agents, a series of allosteric MEK1 inhibitors were designed and synthesized. Based on docking results, multiple optimizations were made on the coumarin scaffold. Some of the derivatives showed excellent MEK1 binding affinity in the appropriate enzymatic assays and displayed obvious inhibitory effects on the ERK pathway in a cellular assay. These compounds also significantly inhibited virus (EV71) replication in HEK293 and RD cells. Several compounds showed potential as agents for the treatment of viral infective diseases, with the most potent compound 18 showing an IC 50 value of 54.57 nM in the MEK1 binding assay.

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