394-08-1

Upstream product

• 581-01-1 4-(4-fluoro-phenyl)-4-oxo-2-phenyl-butyronitrile 

Downstream Products

• 394-05-8 4-(4-fluoro-phenyl)-4-oxo-2-phenyl-butyric acid methyl ester 
• 116776-54-6 6-(4-Fluoro-phenyl)-4-phenyl-4,5-dihydro-2H-pyridazin-3-one 
• 116776-57-9 6-(4-Fluoro-phenyl)-2-methyl-4-phenyl-4,5-dihydro-2H-pyridazin-3-one 
• 116776-66-0 4-[6-(4-Fluoro-phenyl)-4-phenyl-pyridazin-3-yl]-morpholine 
• 116776-69-3 6-(4-Fluoro-phenyl)-4-phenyl-3-piperidin-1-yl-pyridazine 
• 116776-59-1 6-(4-Fluoro-phenyl)-4-phenyl-2H-pyridazin-3-one 
• 116776-61-5 3-Chloro-6-(4-fluoro-phenyl)-4-phenyl-pyridazine 

Relevant academic research and scientific papers

A New Synthetic Route to 4,6-Diarylpyridazinones and Some of their Derivatives

A novel approach to the titled ring system starting from conveniently available chalcones 1 is proposed.It involves a catalysed exchange of hydrogen cyanide between acetone cyanohydrin and 1.The resulting γ-ketonitriles 2 give the expected 4,6-diarylpyrid