3943-80-4

Usage

Chemical Properties

White or almost white crystalline

InChI:InChI=1/C11H14O5/c1-4-16-11(13)7-5-8(14-2)10(12)9(6-7)15-3/h5-6,12H,4H2,1-3H3

Upstream product

• 64-17-5 ethanol 
• 530-57-4 3,5-dimethoxy-4-hydroxybenzoic acid 
• 99463-05-5 (5'-formylfuran-2-yl)methyl 4-acetoxy-3,5-dimethoxybenzoate 
• 39657-47-1 O-acetylsyringic acid chloride 
• 6178-44-5 ethyl 3,4,5-trimethoxybenzoate 

Downstream Products

• 1443-76-1 4-hydroxy-3,5-dimethoxybenzoic acid hydrazide 
• 92727-61-2 4-(2-Dimethylamino-ethoxy)-3,5-dimethoxy-benzoic acid ethyl ester 
• 69114-12-1 1-(4-ethoxycarbonyl-2,6-dimethoxy)phenoxy-2,3-epoxy-propane 
• 161804-41-7 4-((2S,3R,4S,5R,6R)-6-Acetoxymethyl-3,4,5-tris-benzyloxy-tetrahydro-pyran-2-yloxy)-3,5-dimethoxy-benzoic acid ethyl ester 
• 1018438-83-9 4-((3,5,6-trimethylpyrazine-2-yl)methoxyl)-3,5-dimethoxybenzoic acid ethyl ester 
• 1437306-60-9 4-(2-(2-(2-(2-N-Boc-aminoethoxy)ethoxy)ethoxy)ethoxy)-3,5-dimethoxybenzoic acid 
• 1437306-82-5 4-(2-(2-(2-(2-N-Boc-aminoethoxy)ethoxy)ethoxy)ethoxy)-3,5-dimethoxybenzoic acid ethyl ester 
• 1437306-81-4 4-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethoxy)-3,5-dimethoxybenzoic acid ethyl ester 
• 1437306-73-4 C₃₇H₅₀N₄O₁₄ 
• 1437306-72-3 C₃₈H₅₄N₄O₁₄ 
• 1437306-78-9 C₃₂H₄₂N₄O₁₂*C₂HF₃O₂ 
• 1437306-76-7 C₃₃H₄₆N₄O₁₂*C₂HF₃O₂ 
• 1437306-71-2 C₃₈H₅₁N₃O₁₄ 
• 1437306-70-1 C₃₉H₅₅N₃O₁₄ 

Relevant academic research and scientific papers

Composition FOR PREVENTING ALOPECIA AND ACTIVATING HAIR GROWTH

The present invention provides a hair growth promoter comprising as an active ingredient, a compound having a chemical structure of general formula (1) or a pharmacologically acceptable salt thereof. In the general formula (1): R_1 is a saturated or unsaturated straight chain or branched C1-C10 alkyl group or hydroxy alkyl group; R_2 is hydrogen or a saturated or unsaturated straight chain or branched C1-C10 alkoxy or hydroxy alkoxy; X is hydrogen, hydroxy, or a saturated or unsaturated straight chain or branched C1-C10 alkyl group, alkoxy or hydroxyl alkoxy; R_3 and R_4 are each independently selected from R_5, hydrogen, aldehyde, and a saturated or unsaturated straight chain or branched alkyl, alkoxy, or hydroxy alkoxy; R_5 has a structure of # AAA #; R_6 is selected from hydrogen, and a saturated or unsaturated straight chain or branched C1-C10 alkyl, alkoxy, or hydroxy alkoxy; and one of R_3 and R_4 is hydrogen.COPYRIGHT KIPO 2017

Design and synthesis of small-molecule fluorescent photoprobes targeted to aminopeptdase N (APN/CD13) for optical imaging of angiogenesis

We report here the synthesis of a nonpeptide, small-molecule fluorescent imaging agent with high affinity to aminopeptidase N (APN/CD13), a key player in a variety of pathophysiological angiogenic processes. On the basis of a recently described lead structure, we synthesized three putative precursor compounds by introducing polyethylene glycol (PEG) spacers comprising amino groups for dye labeling. Different attachment sites resulted in substantial differences in target affinity, cell toxicity, and target imaging performance. In comparison to bestatin, a natural inhibitor of many aminopeptidases, two of our compounds (22, 23) exhibit comparable inhibition potency, while a third (21) does not show any inhibiting effect. Cell binding assays with APN-positive BT-549 and APN-negative BT-20 cells and the final fluorescent probes Cy 5.5-21 and Cy 5.5-23 confirm these findings. The favorable characteristics of Cy 5.5-23 will now be proven in in vivo experiments with murine models of high APN expression and may serve as a tool to better understand APN pathophysiology.

Selective demethylation and debenzylation of aryl ethers by magnesium iodide under solvent-free conditions and its application to the total synthesis of natural products

An efficient selective demethylation and debenzylation method for aryl methyl/benzyl ethers using magnesium iodide under solvent-free conditions has been developed and applied to the synthesis of natural flavone and biphenyl glycosides. A variety of functional groups including glycoside were tolerated under the reaction conditions. Experimental results indicated that the removal of an O-benzyl group was easier than that of an O-methyl group, regardless of wherever they were meta or para to the carbonyl. Thus selective debenzylation can be achieved for substrates bearing both benzyloxy and methoxy groups.

Orosensory-directed identification of astringent mouthfeel and bitter-tasting compounds in red wine

Application of sequential solvent extraction, followed by HPLC combined with the taste dilution analysis, enabled the localization of the most intense velvety astringent, drying, and puckering astringent, as well as bitter-tasting, compounds in red wine,

Synthesis of Some Furfural and Syringic Acid Derivatives

The formation of several derivatives of furfural and syringic acid, including some incorporating both components, is described.Assignments of the 1H and 13C n.m.r. spectra are also included.