39657-47-1

Basic information

• Product Name: 4-acetoxy-3,5-dimethoxybenzoyl chloride
• Synonyms: 4-acetoxy-3,5-dimethoxybenzoyl chloride;4-Acetyloxy-3,5-dimethoxybenzoic acid chloride
• CAS NO: 39657-47-1
• Molecular Formula: C₁₁H₁₁ClO₅
• Molecular Weight: 258.65504
• EINECS: 254-567-6
• Mol File: 39657-47-1.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 323.7°Cat760mmHg
• Flash Point: 128.7°C
• Appearance: /
• Density: 1.283g/cm³
• Vapor Pressure: 0.000258mmHg at 25°C
• Refractive Index: 1.519
• CAS DataBase Reference: 4-acetoxy-3,5-dimethoxybenzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-acetoxy-3,5-dimethoxybenzoyl chloride(39657-47-1)
• EPA Substance Registry System: 4-acetoxy-3,5-dimethoxybenzoyl chloride(39657-47-1)

Safety Data

• Hazardous Substances Data: 39657-47-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H11ClO5/c1-6(13)17-10-8(15-2)4-7(11(12)14)5-9(10)16-3/h4-5H,1-3H3

Upstream product

• 118-41-2 Eudesmic acid 
• 530-57-4 3,5-dimethoxy-4-hydroxybenzoic acid 
• 6318-20-3 O-acetylsyringic acid 

Downstream Products

• 22802-00-2 1-(4-acetoxy-3,5-dimethoxy-phenyl)-2-diazo-ethanone 
• 63868-68-8 N-(4-Hydroxy-3,5-dimethoxybenzoyl)morpholine 
• 76534-59-3 N,N-bis-(2-hydroxyethyl)-4-acetoxy-3,5-dimethoxybenzamide 
• 3943-80-4 4-hydroxy-3,5-dimethoxybenzoic acid ethyl ester 
• 99463-08-8 (5'-formylfuran-2-yl)methyl 4-hydroxy-3,5-dimethoxybenzoate 
• 530-56-3 syringic alcohol 
• 6638-05-7 2,6-dimethoxy-4-methylphenol 
• 4206-58-0 (E)-sinapinaldehyde 
• 39657-48-2 4-acetoxy-3,5-dimethoxycinnamic acid chloride 
• 110233-74-4 ethyl-(4'-acetoxy-3',5'-dimethoxyphenyl)-prop-2-enoate 
• 90985-68-5 (E)-4-acetoxy-3,5-dimethoxycinnamic acid 
• 1451180-80-5 (α)-2-(4-(5-(1,2-dithiolan-3-yl)pentanoyl)piperazin-1-yl)ethyl 4-acetoxy-3,5-dimethoxybenzoate 

Relevant articles and documents

NOVEL α-TOCOPHEROL DERIVATIVES, AND COSMETIC USES OF THE SAME

The present invention relates to a novel andalpha;-tocopherol derivative compound and cosmetic uses thereof, more specifically, a compound represented by chemical formula 1. The present invention has an antioxidant activity as a novel compound and inhibits the activity of elastase, which is a degradation enzyme of elastin protein related to wrinkle formation of skin, thereby having an effect of alleviating skin wrinkles. In the chemical formula 1, n is 3, and R_1 is each independently hydrogen, a methyl group, or an acetyl group.COPYRIGHT KIPO 2019

NOVEL PHENOLIC ACID DERIVATIVES, AND USES OF THE SAME

The present invention relates to a novel phenolic acid-type derivative compound having whitening and antioxidant activities and a use thereof, and more specifically, to a compound represented by chemical formula 1 below, an isomer thereof, or a salt thereof. Compounds according to the present invention have a tyrosinase-inhibiting skin whitening activity and therefore can be beneficially used in a skin-whitening pharmaceutical composition or cosmetic product, and also have an antioxidant activity and therefore can be used beneficially to prevent or treat skin aging. In the chemical formula 1, n is 0 or 1; X is NH or S; Y is an alkyl group having 1-2 carbon atoms; R is a hydroxyl alkyl, hydroxyl aryl, or hydroxyl alkylaryl group having 1-8 carbon atoms, an amino group, or an amide group; R_2 is H or an alkyl group having 1-3 carbon atoms; and R_3 is H or a methyl group.COPYRIGHT KIPO 2016

Synthesis of selective butyrylcholinesterase inhibitors coupled between α-lipoic acid and polyphenols by using 2-(piperazin-1-yl)ethanol linker

In the previous paper (Bull. Korean Chem. Soc., 2011, 32, 2997), the hybrid molecules between a-lipoic acid (ALA) and polyphenols (PPs) connected with neutral 2-(2-aminoethoxy)ethanol linker (linker-1) showed new biological activity such as butyrylcholinesterase (BuChE) inhibition. In order to increase the binding affinity of the hybrid compounds to cholinesterase (ChE), the neutral 2-(2-aminoethoxy)ethanol (linker 1) was switched to the cationic 2-(piperazin-1-yl)ethanol linker (linker 2). The IC50 values of the linker-2 hybrid molecules for BuChE inhibition were lower than those of linker-1 hybrid molecules (except 9-2) and they also had the same great selectivity for BuChE over AChE (> 800 fold) as linker-1 hybrid molecules. ALA-acetyl caffeic acid (10- 2, ALA-AcCA) was shown as an effective inhibitor of BuChE (IC50 = 0.44 ± 0.24 μM). A kinetic study using 7- 2 showed that it is the same mixed type inhibition as 7-1. Its inhibition constant (Ki) to BuChE is 4.3 ± 0.09 μM.