3944-16-9

Upstream product

• 2123-72-0 1,4-dilithiobutane 
• 80-10-4 diphenylsilyl dichloride 
• 110-52-1 1,4-dibromo-butane 
• 110-56-5 1,4-dichlorobutane 
• 1072-54-4 1,1-dimethyl-1-silacyclopentane 
• 591-51-5 phenyllithium 
• 75-77-4 chloro-trimethyl-silane 
• 2736-09-6 1,1-diphenyl-1-silacyclohexanone-2 
• 2406-33-9 1,1-dichlorosilacyclopentane 

Relevant academic research and scientific papers

?-Silicon-effect-promoted intermolecular site-selective C(sp3)-H amination with dirhodium nitrenes

A dirhodium-catalyzed, ?-selective C-H amination of organosilicon compounds has been developed. Primary C(sp3)-H bonds of silylethyl groups and secondary C(sp3)-H bonds of silacycloalkanes can be selectively converted to C-N bonds at the ?-position of the silicon atoms. The experimental data and theoretical calculations indicate that the strong s-donor ability of the carbon-silicon bonds is responsible for the ?-selectivity. Kinetic isotope effects clearly demonstrate that the C-H bond cleavage step is not turnover-limiting, but selectivity-determining.

SYNTHETIC PROCESS FOR CYCLIC ORGANOSILANES

A process for preparing a cyclic organosilane using a solvent that promotes ring-closure reactions between an organosilane compound and a dihalo organic compound is disclosed. The ring-closure reactions may form a 4-, 5- or 6-member cyclic organosilane. The process involves a mixture including a dihalo organic compound, an organosilane having at least two functional groups, a solvent and magnesium (Mg). The two functional groups in the organosilane may include halogen, alkoxy or a combination thereof. In the presence of Mg, a Grignard intermediate is formed from the dihalo organic compound in the mixture. The solvent favors intra-molecular or self-coupling reactions of the Grignard intermediate. The intra-molecular or self-coupling reaction promotes ring-closure reaction of the Grignard intermediate to form the cyclic organosilane.

UEBER DIE AUSTAUSCHBARKEIT VON METHYL- UND PHENYLGRUPPEN AM SILICIUM VON SILACYCLOPENTAN BEI DER EINWIRKUNG VON ALKYL- UND ARYLLITHIUMVERBINDUNGEN IN DIETHYLETHER ODER TETRAHYDROFURAN

A degenerate ligand exchange, presumably via an ate-complex intermediate, takes place upon treatment of 1,1-dimethyl- (3) and 1,1-diphenyl-silacyclopentane (17) in THF-d8 with perdeuteriomethyllithium (4-d3) or perdeuteriophenyllithium (15-d5), respective