394669-45-5Relevant academic research and scientific papers
Synthesis, characterization and antimicrobial evaluation of novel imines and thiazolidinones
Fuloria, Neeraj Kumar,Singh, Vijender,Yar, Mohammad Shahar,Ali, Mohammed
experimental part, p. 141 - 146 (2009/06/28)
2-(4-Chloro-3-methylphenoxy)acetohydrazide (2) derived from ethyl 2-(4-chloro-3-methylphenoxy) acetate (1) was reacted with different aromatic aldehydes to yield N-(substituted benzylidiene)-2-(4-chloro-3- methylphenoxy)acetamide (3a-e). Cyclization of compound (3a-e) with thioglycolic acid yielded 2-(4-chloro- 3-methylphenoxy)-N-(4-oxo-2-arylthiazolidin-3-yl) acetamide (4a-e). The newly synthesized compounds were characterized on the basis of spectral studies and evaluated for antibacterial and antifungal activities.
